Skip to content

Time and Type Dependent Evaluation of Different Techniques for Correction of Cleft Maxillary Hypoplasia

Time and Type Dependent Evaluation of Different Techniques for Correction of Cleft Maxillary Hypoplasia

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06852196
Enrollment
22
Registered
2025-02-28
Start date
2025-02-21
Completion date
2026-12-01
Last updated
2025-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cleft Lip Palate, Maxillary Hypoplasia, Orthognathic Surgery

Keywords

cleft maxillary hypoplasia

Brief summary

Maxillary hypoplasia in CLP deformities results from congenital reduction in midfacial growth and the effects of the surgical scar from CLP repair.Turvey et al. suggested that this disproportionate jaw growth is the biologic consequence of prior surgical intervention for closure of the soft tissues and is not related to the congenital cleft deformity, Midfacial hypoplasia is commonly treated by performing conventional Le Fort surgery to displace the maxilla anteriorly and stabilization afterward with rigid fixation along with orthodontics treatment. . Midface hypoplasia cleft patient has the following characteristics: concave facial profile, inverted nasal tip, wide alar base, acute nasolabial angle, and excessive exposure of sclera. Intraoral findings are anterior and posterior crossbite, CLP, accentuated curve of Spee, Class III dental malocclusion, multiple missing teeth, oronasal communication, and residual cleft. Speech disturbances are also usually present due to velopharyngeal incompetency and oronasal communication.

Interventions

PROCEDUREorthognathic surgery ,lefort 1,bsso ,DO

Le Fort I osteotomy is often used in the correction of dental occlusion and maxillary hypoplasia in cleft patients. In addition, the osteotomy may also improve patients' facial appearance and self-esteem

Distraction osteogenesis is a surgical technique that uses body's own repairing mechanisms for optimal reconstruction of the tissues.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
12 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Cleft patients either cleft alveolus or cleft alveolus and palate. * Surgically fit patients. * Patients ready for orthognathic assessment undergoing either surgical or orthodontics correction.

Exclusion criteria

* Non- cleft cases . * Previous correction. * History of active infection or underlying disease such as hematologic disorders neoplasm, and immune deficiency. * Patient refused to sign an informed consent.

Design outcomes

Primary

MeasureTime frameDescription
CEPHALOMETRIC1 yearMAXILLARY COMPONENT SNA (degrees) Sella to Nasion to point A angle normal angle is 82 degree plus or minus 3 degree

Secondary

MeasureTime frameDescription
facial canons1 yearthe rule of fifths, which divides the face in the transverse dimension into five equal parts by assuming that the intercanthal distance is equal to the nasal width and widths of the eyes, incorporates orbital and orbito-nasal canons and three equal lengths of the face (the forehead, the nose, and the mouth and chin), as well as the intercanthal distance being equal to the eye fissure length measurement are in cm

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026