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The Validation of a CAD Screening Algorithm Based on Facial Photos in Community Population

The Validation of a Coronary Artery Disease Screening Algorithm Based on Facial Photos in Community Population

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06850233
Enrollment
100
Registered
2025-02-27
Start date
2025-03-04
Completion date
2025-06-24
Last updated
2025-12-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Artificial Intelligence

Brief summary

The purpose of this study is to evaluate the effectiveness of a coronary heart disease screening algorithm based on facial photos in community population.

Interventions

OTHERNo intervention

No intervention

Sponsors

China National Center for Cardiovascular Diseases
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
30 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* Community population with a pre-test probability greater than 5% for coronary artery disease

Exclusion criteria

* Prior percutaneous coronary intervention (PCI) * Prior coronary artery bypass graft (CABG) * The history of heart failure * With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up) * Other situations which make patients fail to be photographed

Design outcomes

Primary

MeasureTime frameDescription
Sensitivity of the algorithmat the end of enrollment (6 months)The sensitivity of the CAD screening algorithm assessed in the group
Specificity of the algorithmat the end of enrollment (6 months)The specificity of the CAD screening algorithm assessed in the group

Secondary

MeasureTime frameDescription
Discriminative capabilitiesat the end of enrollment (6 months)Area under receiver operating curve (AUC) of the algorithm assessed in the group
Positive predictive value (PPV)at the end of enrollment (6 months)PPV of the CAD screening algorithm assessed in the group
Negative predictive value (NPV)at the end of enrollment (6 months)NPV of the CAD screening algorithm assessed in the group
Diagnostic accuracy rateat the end of enrollment (6 months)Diagnostic accuracy rate of the algorithm assessed in the group

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026