Vertical Ramus Osteotomy With Iliac Graft Versus Sagittal Split Osteotomy

Evaluating the Efficacy of Vertical Ramus Osteotomy With Iliac Graft Versus Bilateral Sagittal Split Osteotomy for the Correction of Mandibular Deficiency in Skeletal Class II Cases Management. A Randomized Controlled Trial

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06850194

Enrollment

Registered

2025-02-27

Start date

2025-02-15

Completion date

2026-02-27

Last updated

2025-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular Deficiency

Brief summary

* Patients will be collected from faculty of dentistry * bilateral vertical ramus osteotomy (VRO )with iliac graft group (group I):- 10 patients will be treated via VRO and iliac crest or * bilateral sagital spilt osteotomy (BSSO) group (group II):- 10 patients will be treated via BSSO * All patients will be studied by comprehensive clinical oral and maxillofacial examination and lateral cephalometric radiographic analyses, within 1 week before the surgery (T0), immediately after the surgery (T1), and 6 months after surgery (T2). * All lateral cephalometric radiographs and clinical photographs must be standardized for all cases. * After pre-surgical orthodontic treatment , a lateral cephalograph Will be obtained for planning the surgical movement of both jaws * Surgical models and surgical stent will be fabricated. * All surgical procedures will be performed under nasal intubation and general anesthesia to surgically reposition the maxilla in standard LeFort I setback fosteotomy; the BSSO group will be underwent BSSO, and VRO group will be underwent VRO * The bony segments will be fixed in the new position with the use of custom made plates (specific for each patient )

Interventions

PROCEDUREvertical ramus osteotomy with iliac graft

in the VRO group all patient will undergo vertical ramus osteotomy surgery with iliac graft to correct the sever mandibular defficiency

PROCEDUREbilateral sagittal splitting osteotomy

all patients in this group will undergo to bilateral sagittal split osteotomy to correct the sever mandibular deficiency

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients with age above 18 years old suffered from skeletal class II with severe mandibular deficiency

Exclusion criteria

* patients with chin deviation, * severe temporomandibular joint (TMJ) symptoms. * Sever periodontal disease * pregnancy, * previous mandibular surgery, * inability to follow-up for the study protocol

Design outcomes

Primary

Measure	Time frame	Description
skeletal stability	6 months	Skeletal stability will be assessed by lateral cephalometric x-ray. It will be done pre operatively, immediate postoperative, and 6 months later

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026