Burns
Conditions
Brief summary
Fourty patients who have total body surface area ranged from 20% to 35% of burn, anemic and 8th to 16th week post burn will participate in this study, the patients will be randomly divided into two equal groups (20 patients for each group): Group A (Experimental Group) (Aerobic exercise and medical treatment): Group B ( Control Group) (Medical treatment group):
Interventions
PROCEDUREAerobic exercise and medical treatment
Aerobic exercise training was done for 30 minutes, day after day (3 sessions weekly) for 6 weeks. Each session started by warming up phase that was walking on treadmill for 5 minutes at 20% of target heart rate. Active phase after warming up was walking on treadmill for 20 min at 50-70 % of target heart rate. And cooling down phase after the active phase of exercise was walking on treadmill for 5 minutes at 20 % of the target heart rate
DIETARY_SUPPLEMENTMedical treatment group
patient received supplement in the form of one capsule daily, that contain iron supplement (10 mg) and multi vitamins (B1=0.6 mg;, B2=0.6 mg; B6=0.6 mg; B12= 1.2 mc and C=30 mg) as well as essential trace elements (Zinc=5 mg; Copper=0.44 mg; Folic acid=200 mc and Biotin=12 mc
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
The subject selection will be according to the following criteria: 1. Ages of patients will be ranged from 20 to 35 years. 2. All patients underwent severe burn with TBSA ranged from 20% to 35%. 3. 8 th to 16th week post burn. 4. All patients will be referred with persisted anemia by a surgeon before starting the study procedure. 5. All patients will enter the study having their informed consent
Exclusion criteria
The potential participants will be excluded if they meet one of the following criteria: 16 1. Patients with persisted pre burn anemia associated with systematic chronic disease such as coronary artery disease or chronic kidney disease. 2. Patients with pre burn persisted anemia associated with autoimmune disease such as Rheumatoid arthritis, Systemic lupus erythematosus ,Vasculitis, Sarcoidosis, Inflammatory bowel disease (IBD). 3. Unevaluated cardiac arrhythmia, Chronic bronchitis, poorly controlled type 1 diabetes, Extreme morbid obesity, Extreme underweight body mass index less than 12, Poorly controlled hypertension, Poorly controlled seizure disorder, Poorly controlled hyperthyroidism, Orthopedic limitation as fracture, .
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Red blood cells | pre intervention and re assessed after 6 weeks of treatment | It will be drawn by the doctor and a specialist nurse. Red blood cell (RBC) count measures the number of red blood cells in your blood. The unit of measurements is cell per microliter. Normal RBC ranges are: Male: 4.7 to 6.1 million cells per microliter (cells/mcL) Female: 4.2 to 5.4 million cells/mcL. |
| Hemoglobin | pre intervention and re assessed after 6 weeks of treatment | It will be drawn by the doctor and a specialist nurse. The unit of measurement is grams/deciliter. Normal range for men is , 13.2 to 16.6 grams per deciliter. Normal range for women is, 11.6 to 15 grams per deciliter. |
| Hematocrit | pre intervention and re assessed after 6 weeks of treatment | It will be drawn by the doctor and a specialist nurse. The hematocrit is the percentage of packed RBCs in the whole blood. The hematocrit has the implied units of L/L, although it is usually reported as a percent. Normal range for Males: 41% to 50%. Normal range for Females: 36% to 44%. |
Countries
Egypt
Outcome results
None listed