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Impact of Combined Aerobic and Resistance Exercise on Autonomic Function and Cardiopulmonary Endurance in Obese College Students

Impact of Combined Aerobic and Resistance Exercise on Autonomic Function and Cardiopulmonary Endurance in Obese College Students

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06848985
Enrollment
60
Registered
2025-02-27
Start date
2023-09-02
Completion date
2023-12-24
Last updated
2025-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aerobic Exercise Combined with Resistance Exercise, Obese College Students

Keywords

Aerobic exercise combined with resistance exercises, Cardiorespiratory endurance, Autonomic function, Obese college students

Brief summary

This study explores the potential link between aerobic exercise combined with resistance training and improvements in cardiopulmonary function in obese individuals, focusing particularly on the influence of autonomic nerve function. By examining the effects of combined exercise on obese college students, this research aims to elucidate the critical role that autonomic nerve function improvement plays in enhancing cardiopulmonary function in this demographic. The study primarily utilized a combined exercise regimen of aerobic and resistance exercises, conducted three times a week over a period of 16 weeks. One session was held during class hours, with the remaining two sessions scheduled during free time in the university gym. Aerobic exercises included the use of treadmills and elliptical machines, with intensity maintained at 60%-70% of the maximum heart rate (calculated as 220 minus age), for a total of 40 minutes per session (5 minutes of warm-up, 30 minutes of main exercise, and 5 minutes of cool-down). Heart rate monitors were used to ensure the intensity was maintained; resistance exercises involved gym equipment and bodyweight exercises, including the use of a pec deck machine, lat pull-downs, chest presses, bicep curls, tricep extensions, leg curls, and leg presses. The intensity of resistance exercises was set at about 65%-70% of one repetition maximum (1RM), with each session consisting of three sets of 6-8 repetitions and lasting for 30 minutes.

Interventions

BEHAVIORALAerobic combined with Resistance exercise

Participants are required to perform aerobic and resistance exercises. Aerobic exercises included the use of treadmills and elliptical machines, with intensity maintained at 60%-70% of the maximum heart rate (calculated as 220 minus age), for a total of 40 minutes per session (5 minutes of warm-up, 30 minutes of main exercise, and 5 minutes of cool-down). Heart rate monitors were used to ensure the intensity was maintained; resistance exercises involved gym equipment and bodyweight exercises, including the use of a pec deck machine, lat pull-downs, chest presses, bicep curls, tricep extensions, leg curls, and leg presses. The intensity of resistance exercises was set at about 65%-70% of one repetition maximum (1RM), with each session consisting of three sets of 6-8 repetitions and lasting for 30 minutes.

Sponsors

Capital University of Physical Education and Sports, China
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Intervention model description

Obese college students aged 18-22 were recruited from a university in Beijing to participate in a public elective course on exercise for weight loss and slimming at the Capital University of Physical Education and Sport (CUPES). Ultimately, 60 students who met these criteria were selected for the study, divided into an experimental group of 30 and a control group of 30. The study primarily utilized a combined exercise regimen of aerobic and resistance exercises, conducted three times a week over a period of 16 weeks. The control group maintained their normal physical activity levels without any additional intervention.

Eligibility

Sex/Gender
ALL
Age
18 Years to 22 Years
Healthy volunteers
Yes

Inclusion criteria

* Obese college students aged 18-22 were recruited from a university in Beijing to participate in a public elective course on exercise for weight loss and slimming at the Capital University of Physical Education and Sport (CUPES). The inclusion criteria included a BMI of ≥28 kg/m\^2, no history of chronic diseases such as cardiovascular or metabolic diseases, no psychiatric conditions (e.g., depression, anxiety disorder, obsessive-compulsive disorder), and no physical disabilities or movement disorders (such as bone and joint diseases).

Exclusion criteria

* The

Design outcomes

Primary

MeasureTime frameDescription
Autonomic functionFrom enrollment to the end of treatment at 16 weeksAutonomic function was assessed using the Pushikang FLY-2 autonomic physiological monitor. Participants were required to abstain from caffeinated and alcoholic beverages for 12 hours and from strenuous physical activity for 48 hours prior to the test. The testing was conducted between 8:00 a.m. and 11:00 a.m. in a controlled environment with temperatures maintained at 22-24°C. The test duration was 5 minutes, during which participants sat quietly and refrained from speaking. Autonomic nerve function parameters were recorded using finger photoplethysmography to measure pulse wave changes in a resting state. Data was processed using Beijing Fourier's autonomic nerve response analysis software (ANS-1, V6.6). Time-domain analysis focused on the mean interval between heartbeats to reflect sympathetic/vagal modulation, and the variance of these intervals indicated the overall variability of cardiac function, providing critical prognostic information.
Cardiorespiratory enduranceFrom enrollment to the end of treatment at 16 weeksCardiopulmonary function was evaluated using the cardiopulmonary exercise test (CPET, Schiller) on a Rehab-B exercise treadmill. To ensure test accuracy, participants were instructed to refrain from physical activity on the day prior to the test and to avoid alcohol, caffeinated beverages, and food for 8 hours before testing and during the first 3 hours of the test day. The exercise commenced with a 3-minute rest followed by a gradual load phase, allowing participants to reach voluntary fatigue within 8 to 12 minutes, and then continue at maximum tolerance for an additional 3 minutes. The exercise protocol followed the Bruce protocol, with incremental loads adjusted for gender: 25 W/min for males and 15 W/min for females.

Secondary

MeasureTime frameDescription
The Functional Movement Screen (FMS) scoreFrom enrollment to the end of treatment at 16 weeksThe Functional Movement Screening (FMS) is a standardized tool used to assess the functional motor abilities of individuals. It consists of seven tests (squatting, stepping, lunging, reaching, leg raising, push-up, and rotary stability) that balance flexibility and stability, allowing medical and fitness professionals to identify problems such as weakness, imbalance, asymmetry, and movement limitations. In the FMS, each action is scored from 0 to 3: a score of 3 indicates the individual can perform the movement standardly and stably without compensation; a score of 2 signifies that the movement can be completed, albeit with some instability or compensatory behavior; a score of 1 indicates an inability to perform the movement according to the standards. Research has shown that lower FMS scores correlate with a higher risk of injury. Typically, a threshold score of 14 is used, with individuals scoring below this level considered at greater risk of injury.
Body compositionFrom enrollment to the end of treatment at 16 weeksBody composition was assessed using the InBody760 (Ver. LookinBody120.4.0.0.7) bioelectrical impedance analyzer. Measurements were taken in the early morning, with subjects fasting and in a controlled temperature environment (22-24℃), providing immediate readings of body mass index (BMI), body fat percentage, waist-to-hip ratio, visceral fat area.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026