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Prevention Ambassadors: Intervention to Promote HIV Service Engagement in the Networks of SSP Clients

Prevention Ambassadors: an HIV Self-testing Intervention to Promote HIV Service Engagement in the Networks of SSP Clients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06848686
Enrollment
210
Registered
2025-02-27
Start date
2025-02-03
Completion date
2027-02-01
Last updated
2026-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV

Brief summary

HIV testing and service uptake are infrequent among people who use drugs (PWUD) in the United States. In partnership with a community-based syringe service program (SSP), this project will develop the SSP-based "Prevention Ambassadors" (PA) intervention to promote HIV testing and service uptake among PWUD via the secondary distribution (i.e., peer delivery) of HIV self-testing (HIVST) kits with local HIV service information and referrals to HIV service navigation in the social networks of SSP clients (i.e., PWUD). The PA intervention will then be piloted to assess its preliminary effects, acceptability, and feasibility among PWUD in the Ending the HIV Epidemic priority jurisdiction of Riverside County, California.

Interventions

BEHAVIORALPrevention Ambassadors

Delivery of prevention supplies and information on local services plus training to build the capacity of PWUD to distribute HIV self-testing (HIVST) kits with information and referrals to other PWUD in their social networks to promote HIV testing and HIV service engagement among PWUD.

BEHAVIORALSSP Standard of Care

Delivery of prevention supplies and information on local services.

Sponsors

San Diego State University
Lead SponsorOTHER
University of California, San Diego
CollaboratorOTHER
University of California, Riverside
CollaboratorOTHER
Dap Health
CollaboratorOTHER
National Institute on Drug Abuse (NIDA)
CollaboratorNIH

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Index Participant Inclusion Criteria: * Being greater than or equal to 18 years old * Reporting drug use (past month) * Having other people who use drugs (PWUD) in one's social network * Being willing to talk about HIV testing and services with at least 2 PWUD in their networks and attempt to refer them to the study * Speaking English fluently Peer-Recruit Participant Inclusion Criteria: * Being greater than or equal to 18 years old * Reporting drug use (past 3 months) * Being recruited by an index participant (evidenced by presenting the coupon used to recruit them) * Speaking English fluently

Exclusion criteria

\- Persons who participated in formative study activities related to the development of the PA intervention will not be eligible to participate.

Design outcomes

Primary

MeasureTime frameDescription
HIV testing (past 3 months)3-month follow-upSelf-reported via survey and abstracted from medical record
Linkage to PrEP/HIV care (past 3 months)3-month follow-upSelf-reported via survey and abstracted from medical record
PrEP/ART uptake (past 3 months)3-month follow-upSelf-reported via survey and abstracted from medical record

Secondary

MeasureTime frameDescription
PA Acceptability (Peer-Recruit Participants)BaselineSelf-reported via survey
PA Acceptability (Index Participants)3-month follow-upSelf-reported via survey
PA Feasibility (Peer-Recruit Participants)BaselineSelf-reported via survey
PA Feasibility (Index Participants)3-month follow-upSelf-reported via survey

Countries

United States

Contacts

CONTACTHeather Pines
hpines@sdsu.edu619-594-2481
PRINCIPAL_INVESTIGATORHeather A Pines

San Diego State University

PRINCIPAL_INVESTIGATORAngela R Bazzi

University of California, San Diego

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026