Binge Eating, Binge-Eating Disorder, Obesity, Type 2 Diabetes Mellitus
Conditions
Brief summary
Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults. Though numerous factors affect these disparities, one modifiable risk factor may be that of binge eating (BE), which increases risk for binge-eating disorder (BED), which is associated with severe obesity, and often precedes a T2DM diagnosis, beginning in childhood or adolescence. Nearly 30% of Black women with obesity report binge eating episodes. Furthermore, given that binge and overeating may disparately increase the odds of obesity in Black adults (15-fold increase vs. 6-fold increase in White adults), reducing this behavior will be critical to prevent continued disparities in T2DM diagnosis. Given that Black women have the highest rates of obesity in the nation (57%), report disparate rates of weight gain between young adulthood and mid adulthood, and report disparate rates of emotional eating in adolescence, which is a risk factor for BE, one pathway to reducing disparities in T2DM risk in Black women may be to reduce binge eating and prevent weight gain in emerging adulthood (ages 18-25).
Detailed description
Aim 1. Use formative research to gather recommendations to Tailor AAT+DPP to Black Emergent Adult (EA) Women (Year 1). Aim 2. Utilize community-engaged and user-centered design methods to adapt a mobile intervention to prevent T2DM in Black women at risk for BED (Year 2). Aim 3. Conduct a pilot randomized trial to examine the feasibility and acceptability, and preliminary efficacy of the adapted AAT+ DPP intervention (Years 3-4; Analysis Year 5).
Interventions
BEHAVIORALAppetite Awareness Training (AAT)
Participants will receive the AAT delivered as 16 core sessions over six months as well as six maintenance sessions over the course of 12 months.
BEHAVIORALDiabetes Prevention Program (DPP)
Participants will receive the DPP delivered as 16 core sessions over six months as well as six maintenance sessions over the course of 12 months.
Sponsors
University of North Carolina, Chapel Hill
American Diabetes Association
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 25 Years
Healthy volunteers
Yes
Inclusion criteria
* Black women * between 18-25 years of age * BMI ≥ 25 kg/m\^2 * At least one binge eating episode weekly * Prediabetic * Have access to a smartphone
Exclusion criteria
* Have no internet access * Currently type 2 diabetic * Currently pregnant * Are in substance use treatment * Have received prior or planned bariatric surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in number of Binge Eating Episodes from Baseline to Month 6 | Baseline, 6 months | Participants will self-monitor and complete surveys on binge eating episodes. |
| Change from Baseline to Month 6 in weight regain | Baseline, 6 months | Participant body weight will be measured by trained research staff using calibrated digital scales. Participants will be in light indoor clothing, with pockets emptied, and belts and shoes removed. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Inflammatory Biomarkers for T2DM from Baseline to Month 6 | Baseline, 6 months | Participants will provide plasma samples to examine the risk for type 2 diabetes mellitus. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORRachel Goode, PhD,MPH,LCSW
University of North Carolina, Chapel Hill
Outcome results
None listed