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Smartphone-Based Use of Phonocardiography Technique for Estimating Heart Rate and Heart Rate Variability: Performance Study

Smartphone-Based Use of Phonocardiography Technique for Estimating Heart Rate and Heart Rate Variability: Performance Study

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06848179
Enrollment
50
Registered
2025-02-26
Start date
2025-03-31
Completion date
2025-07-31
Last updated
2025-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise

Keywords

Auscultation, Smartphone, Heart Sounds, Heart Auscultation, Phonocariodgraphy

Brief summary

This study aims to investigate the use of heart sound recordings, or phonocardiograms, recorded with smartphones' built-in microphones and accessory microphones to estimate heart rate (HR) and heart rate variability (HRV). HR refers to the number of heart beats per minute, while HRV refers to the variation in the intervals between heart beats. Participants will have their heart sounds (phonocardiograms) recorded before and after exercise, and electrocardiogram (ECG) and photoplethysmogram (PPG) data recorded before, during, and after exercise to induce a wide range of HR. Researchers will match the phonocardiograms, ECG, and PPG data to create a database for use in future training and testing of algorithms (including artificial intelligence (AI)).

Interventions

DIAGNOSTIC_TESTComputer algorithms

Collection of computer algorithms called ausculto® that is designed to perform heart sound analysis to estimate heart rate and heart rate variability

BEHAVIORALExercise

Participants will be requested to exercise to raise their HR over the resting range while heart-related physiological signals are collected.

Sponsors

Laboratory of Data Discovery for Health
CollaboratorUNKNOWN
The University of Hong Kong
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 69 Years
Healthy volunteers
Yes

Inclusion criteria

* With no tattoos on their body where a smartwatch will be placed

Exclusion criteria

* Not ready to undertake physical activity as assessed by the Physical Activity Readiness Questionnaire (PAR-Q) derived from the Canadian Society for Exercise Physiology * Implanted active medical devices in the torso, such as pacemakers and defibrillators * Failure to collect baseline heart sound time series from ECG or both smartphone and auscultation pin before exercise

Design outcomes

Primary

MeasureTime frameDescription
HR estimationDay 0The algorithm will estimate participants' HR from phonocardiograms at multiple timepoints. The concordance correlation coefficient, mean bias, and limits of agreement will be calculated for HR with ECG-derived HR as the gold standard.
HRV estimationDay 0The algorithm will estimate participants' HRV from phonocardiograms at multiple timepoints. The absolute difference (error) in HRV estimation will be calculated with ECG-derived HRV as the gold standard.

Secondary

MeasureTime frameDescription
Participants' comfort level for devices used in this studyDay 0A survey will be given to participants after heart data collection to evaluate their preferences and comfort level when using the different devices to measure HR and HRV.

Contacts

Primary ContactJoshua Ho, Ph.D.
jwkho@hku.hk+852 3917 9512

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026