Artificial Intelligence (AI), Atrial Arrhythmias, Atrial Fibrillation (AF), Electrocardiogram, Premature Atrial Complexes
Conditions
Brief summary
Our study aimed to use an AF-predict AI-ECG alert system to help physicians identify patients who need to wear a continuous cardiac rhythm monitor for new diagnoses of atrial fibrillation (AF), atrial flutter (AFL), or atrial arrhythmia with high AF risk, including premature atrial complexes (PAC) ≥ 500/24hr, burst PACs \> 20 beats, non-sustained AF/AFL.
Interventions
OTHERAF-predict AI-ECG alert system guided management
AF-predict AI-ECG alert system
Sponsors
National Defense Medical Center, Taiwan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Days to 85 Days
Healthy volunteers
No
Inclusion criteria
* Patients in the inpatient department or the outpatient department * Patients need to have at least one electrocardiogram within one year
Exclusion criteria
* Diagnosis of atrial fibrillation/atrial flutter * History of atrial fibrillation/atrial flutter catheter ablation * Patients with cardiac implantable electronic devices * Any documented electrocardiogram showed atrial fibrillation/atrial flutter and pacing rhythm * History of received rhythm control medications for atrial arrhythmia, including Class I and Class III antiarrhythmic drugs * Any reasons indicate for anti-coagulant agents, including vitamin K antagonist and non-vitamin K antagonist oral anticoagulant
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Latent atrial fibrillation | Within 90 days after enrollment. | The primary outcome, latent atrial fibrillation, is a composite of new diagnoses of AF/AFL, atrial arrhythmia with high AF risk, including PACs ≥ 500/24hr, burst PACs \> 20 beats, and non-sustained AF/AFL, within 90 days after enrollment. The results will be demonstrated as the rate of diagnoses of latent atrial fibrillation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Antiarrhythmic treatment | Within 180 days after enrollment. | Antiarrhythmic treatment may include newly prescribed beta-blockers or non-dihydropyridine calcium channel blockers, class Ia, Ic, and III antiarrhythmic drugs, and catheter ablation. Physicians can determine whether a patient requires antiarrhythmic treatment through clinical practice. The outcome is the rate of initiation of antiarrhythmic treatment. |
| 90-days New diagnoses of atrial fibrillation/atrial flutter | Within 90 days after enrollment. | New diagnoses of atrial fibrillation or atrial flutter are defined as those documented by a 12-lead electrocardiogram or by continuous cardiac rhythm monitoring for ≥ 30 seconds. The result will be presented as the rate of new diagnoses of atrial fibrillation or atrial flutter. |
| Atrial arrhythmia with high AF risk | Within 90 days after enrollment. | Atrial arrhythmia with high AF risk is defined by the following criteria: premature atrial complexes more than 500 beats in 24 hours as recorded by a continuous cardiac rhythm monitor; burst premature atrial complexes exceeding 20 beats as documented in a continuous cardiac rhythm monitor or a 12-lead electrocardiogram, or documented non-sustained AF/AFL in either a continuous cardiac rhythm monitor or a 12-lead electrocardiogram. The result will be presented as the rate of diagnoses of atrial arrhythmia with high AF risk. |
Countries
Taiwan
Contacts
Primary ContactChin Lin, PhD
Backup ContactChiaoChin Lee, MD
Outcome results
None listed