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Predictors of Clinical and Neurological Outcome in Traumatic Posterior Fossa Epidural Hematoma

Predictors of Clinical and Neurological Outcome in Traumatic Posterior Fossa Epidural Hematoma

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06847516
Enrollment
94
Registered
2025-02-26
Start date
2025-03-01
Completion date
2026-05-01
Last updated
2025-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Posterior Fossa Epidural Hematoma

Brief summary

The posterior fossa is a small space in the skull containing the brainstem and cerebellum. If a mass such as a hemorrhage grows in this region, particularly the brainstem and 4th ventricle, it can block the normal flow of cerebral spinal fluid leading to hydrocephalus, increased intracranial pressure.Posterior fossa extradural hematoma (PFEDH) is a rare neurosurgical entity, resulting in rapid clinical deterioration. The accumulation of blood in a potentially small space between the dura and occipital bone cause compression of the brain stem.These hematomas constitute almost 4% to 12.9% of all extradural hematoma cases. The extradural hematomas of the posterior fossa may be categorized as acute or delayed defined with respect to the brainstem compression appearing within or after 24 hours of injury, respectively. Acute PFEDH is characterized by medullar failure, occipital trauma associated with severe pain in the nuchal area, altered consciousness followed by rapid brainstem compression, respiratory depression, and subsequent death if not treated timely and appropriately.Whereas, headache, neck pain, dysfunction of lower cranial nerve in response to PF lesions and cerebellar signs. The clinical features of PFEDH are nonspecific; it may include occipital headache, vomiting due to raised intracranial pressure, and decreased consciousness level leading to death. The skull fractures must be considered as a predisposing factor for the development of delayed extradural hematomas. The aim of this study is : * To evaluate the outcome of patients with traumatic post fossa Epidural hematoma * list the predictors of outcome for patients with post fossa Epidural hematoma

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Any age * Traumatic Posterior fossa epidural hematoma

Exclusion criteria

* Spontaneous type of epidural heamatoma

Design outcomes

Primary

MeasureTime frameDescription
The postoperative GOS score30 dayhe Glasgow outcome scale (GOS). GOS score four and five were considered good recovery outcomes, GOS 2 and 3 indicated poor outcomes, and OS one indicated mortality.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026