Efficacy of US-guided TFPB in Open Gynecologic Surgery

Efficacy of Ultrasound-guided Transversalis Fascia Plane Block (TFPB) in Controlling Postoperative Pain After Transverse Incision in Gynecologic Surgery

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06847022

Enrollment

Registered

2025-02-26

Start date

2024-11-04

Completion date

2025-08-30

Last updated

2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic Surgical Procedures, Transversalis Fascia Plane Block

Keywords

Transversalis fascia plane block, open gynecologic surgery, transverse incision

Brief summary

Transversalis fascia plane block (TFPB) has been studied and has shown to be very effective in controlling postoperative pain after caesarean section but has not been studied in open gynecologic surgery with transverse incision. Inadequate pain control after open gynecologic surgery is associated with negative consequences such as chronic pelvic pain. The investigators aimed to evaluate the efficacy of TFPB in controlling postoperative pain after open gynecologic surgery with transverse incision.

Detailed description

A randomized controlled trial study in which comparing US-guided TFPB vs conventional pain control in open gynecologic surgery

Interventions

PROCEDUREUS-guided transversalis fascia plane block

US-guided bilateral transversalis fascia plane block, using Sonotap 110 mm and 0.25% bupivacaine 20 ml on each side, will be done after wound closure.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients who undergoing open gynecologic surgery under general anesthesia * Age 18 - 70 years * ASA Physical status I-III * Transverse incision

Exclusion criteria

* Creatinine clearance is less than 30 ml/min * Body weight \< 50 kg * Re-open surgery * Persistent chronic pelvic pain * Allergic to medications used in this study

Design outcomes

Primary

Measure	Time frame
Postoperative 24 hours morphine requirement	24 hours

Secondary

Measure	Time frame	Description
postoperative pain score	1 hour, 6 hours, 24 hours	—
Side effects from postoperative opioids	24 hours	nausea vomiting, itching, respiratory depression
Incidence of chronic pelvic pain	3 months	—

Countries

Thailand

Contacts

PRINCIPAL_INVESTIGATORAssist. Prof. Dr. Preeyaphan Arunakul, M.D., FRCAT

Faculty of Medicine, Thammasat University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: May 15, 2026