Association Between ΜFR and CABG Outcomes

Association Between Murray Law-Based Angiography-Derived Fractional Flow Reserve and Outcomes After Coronary Artery Bypass Grafting

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06844721

Enrollment

945

Registered

2025-02-25

Start date

2008-01-01

Completion date

2026-12-31

Last updated

2025-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Bypass Graft Surgery (CABG)

Keywords

quantitative flow reserve, coronary artery bypass graft surgery (CABG), graft patency, clinical outcomes

Brief summary

The goal of this observational study is to evaluate the association between Murray law-based quantitative flow reserve and outcomes after coronary artery bypass graft surgery.

Detailed description

The goal of this observational study is to evaluate the association between Murray law-based quantitative flow reserve and outcomes after coronary artery bypass graft surgery. By constructing registry database during 10-year periods, several types of study objectives including 'graft patency' and 'long-term clinical outcomes' will be evaluated.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Inclusion criteria

1. patients who underwent isolated off-pump CABG for 3-vessel disease, 2. patients who underwent preoperative coronary angiography that fits for μFR analysis,

Exclusion criteria

1. Patients who underwent on-pump CABG 2. Patients in whom quality of preoperative coronary angiography did not fit for μFR analysis

Design outcomes

Primary

Measure	Time frame	Description
Graft patency rate	1 year after surgery	1 year graft patency rate after surgery
Number of participants with Long-term all-cause mortality	From date of enrollment (operation) until the date of death from any cause, assessed up to 15 years).	All-cause mortality indicates death from any cause during follow-up

Secondary

Measure	Time frame	Description
Number of partipiciants with major adverse cardiac events	From date of enrollment (operation) until the date of first documented major events or date of death from any cause, whichever came first, assessed up to 15 years	MACE includes death, repeat revascularization and non-fatal myocardial infraction

Countries

South Korea

Outcome results