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The Development of Diagnosis and Prognosis Predictive Model for Peripheral Nerve Disease

The Development of Diagnosis and Prognosis Predictive Model for Peripheral Nerve Disease Using Big Data From Magnetic Resonance Neurography: A Multicenter Cohort Study(MRN-PND)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06843642
Enrollment
10000
Registered
2025-02-25
Start date
2015-01-01
Completion date
2025-01-01
Last updated
2025-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral Nerve Disease

Brief summary

This is a retrospective observational cohort study (MRN-PND), aiming to explore the utility of contrast-enhanced MRN (ceMRN) compared to plain MRN in diagnosing peripheral nerve diseases and predicting the prognosis of patients with these conditions. Additionally, artificial intelligence (AI) methods are employed to enhance the diagnostic accuracy of MRN for peripheral nerve diseases and to precisely predict disease outcomes.

Interventions

None listed

Sponsors

Wuhan No.1 Hospital
CollaboratorOTHER
University Hospital Heidelberg
CollaboratorOTHER
West China Hospital
CollaboratorOTHER
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

1. Patients who underwent MRN scanning at Wuhan Union Hospital between January 2015 and January 2025; 2. Age \> 18 years; 3. Definitive clinical diagnosis (either healthy individuals or patients with a specific condition).

Exclusion criteria

: 1. Poor quality of imaging; 2. Incomplete clinical data or loss to follow-up; 3. Unclear clinical diagnosis.

Design outcomes

Primary

MeasureTime frameDescription
Correlation analysis of MR information and diagnosis outcome0.5 yearThe indicator is the area under the curve of the predict diagnosis outcome.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026