Food Selection, Weight Loss
Conditions
Keywords
GLP-1, Weight Loss, Virtual Reality, Food behavior
Brief summary
In recent years, GLP-1 medications have become a widely employed approach by physicians to address weight concerns in patients and lead to weight loss. Little is known, however, about how these medications may alter an individual's attitude towards food, food reactivity, or the specific types and amounts of foods an individual will choose. The purpose of this study is to observe the changes an individual experiences in their relationship and reaction to food and in their food selection prior to or within the first two weeks of taking GLP-1 medication to after three months on the medication. The researchers of this study believe that an understanding of such changes can inform questions seeking to ensure maintenance of appropriate nutrient balance within individuals on weight loss medications.
Interventions
OTHERGLP-1 Medication Initiation
One visit before starting GLP-1 medication and one visit 3 months after. No other changes administered between visits.
Sponsors
Penn State University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (18+) with overweight or obesity (BMI \>25 kg/m2) * Not currently taking an incretin-based medication at baseline * Recently (within two weeks) prescribed a GLP-1, can be included if they have a obesity-related co-occurring condition (diabetes, hypertension, cardiovascular disease, dyslipidemia) * Have had no prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy. * Fluent in English
Exclusion criteria
* Adults (18+) without overweight or obesity * \<18 years of age at time of testing * Adults not taking a GLP-1 Medication * Adults taking a compound GLP-1 * Adults on GLP-1 medication for longer than 2 weeks at baseline * Have had a prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy. * Not fluent in English
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from Baseline in Variety of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months |
| Change from Baseline in Total Weight of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months |
| Change from Baseline in Total Calories of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months |
| Change from Baseline in Energy Density of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Baseline Three-Factor Eating Questionnaire Score at 3 Months | Baseline and 3 months | Rated on a scale of 1-4 with 1 being Definitely false and 4 being Definitely true; 3 subscales, higher scales on each means greater expression of that behavior |
| Change in Baseline Buffet Food Liking Scores at 3 Months | Baseline and 3 months | Rated on a 0-100 scale with 0 being Dislike extremely and 100 being Like extremely; high scores mean greater liking of the food |
| Change in Baseline General Food Craving-Trait Scale Score at 3 Months | Baseline and 3 months | Rated on a 0-5 scale with 0 being Never/not applicable and 5 being Always; higher scores mean more food dependent |
| Change in Baseline Weight Watchers Food Noise Score at 3 Months | Baseline and 3 months | Based on participant's answers to the WW Food Noise questionnaire; Scale of 1-5, 1 being strongly disagree and 5 being strongly agree; Higher scores mean more food noise |
| Change in Baseline 9-question External Food Cue Responsiveness Questionnaire Score at 3 Months | Baseline and 3 months | Answers are on a 1-4 scale with 1 being Rarely and 4 being A lot; higher scores suggest more external food cue reactivity |
| Change in Baseline Adult Eating Behavior Score at 3 Months | Baseline and 3 months | Answers on a 1-5 scale with 1 being Strongly disagree and 5 being Strongly agree; 8 subscales, high scores indicate greater expression of subscale measure |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change in Baseline BMI at 3 Months | Baseline and 3 months | Calculated from height and weight collected at the end of both sessions |
Countries
United States
Contacts
Primary ContactChristina M Blackmon
Outcome results
None listed