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Effect of Botulinum Toxin a Injection in Treatment of Recession RT1 and RT2

Effect of Botulinum Toxin -A Injection in Mentalis Muscle with Coronally Advanced Flap and De-epithelized Free Gingival Graft in Treatment of RT1 , RT2 Gingival Recession _Randomized Control Trial

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06842290
Enrollment
28
Registered
2025-02-24
Start date
2025-04-04
Completion date
2026-10-16
Last updated
2025-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession

Brief summary

The goal of this study type: clinical trial\] is to learn the effect of Botulinum Toxin \_A injection in treatment of RT1andRT2 Gingival recession in lower anterior teeth . Primary outcome is keratinzed tissue width. Researchers will compare Coronally Advanced flap with De-epithelized free gingival graft and Botulinum toxin-A injection in Mentalis muscle with coronally advanced flap with De-epithelized free gingival graft alone . The outcome will be measured at baseline, after 3 months and after 6 mobths \_medical history * 3 mm horizontal incisions, then two vertical incisions * deepitheliztion of anatomical papillae * superficial and deep incisions * harvesting DFGG * Suturing * BOTOX injection

Interventions

Botulinum toxin-A Injection Mentalis muscle in lower anterior teeth

Coronally Advanced Flap andDe-epithelized Free Gingival Graft

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Single or multiple RT1, RT2 GR patient * patients ≥18 years * systemically healthy, full mouth plaque score, full mouth bleeding score ≤ 15% after phase I therapy * clinical indication and/or patient request for recession coverage * well motivated patients, maintaining oral hygiene throughout study

Exclusion criteria

* Pregnant or lactating women * Smokers' patients * Teeth with cervical restorations/abrasion. * Patients had a systemic condition affect blood components and healing

Design outcomes

Primary

MeasureTime frame
Keratinized tissue widthMeasured at baseline ,3months ,6 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026