Plaque Reduction Sesame-based Oil

The Plaque Reducing Efficacy of Oil Pulling with Sesame-Based Oil. a Randomized-controlled Clinical Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06841380

Enrollment

Registered

2025-02-24

Start date

2023-04-25

Completion date

2023-06-22

Last updated

2025-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental Plaque, Gingivitis, Oral Microbial Colonization

Brief summary

The goal of this clinical trials to learn about potential additives in reducing dental plaque. The main questions it aims to answer is: • is there a difference in the plaque reducing effect of oil pulling with sesame-based oil compared to rinsing with distilled water? Participants will rinse with 15 ml of their allocated liquid for 15 min every morning for 8 weeks. Researchers will compare sesame-based oil against distilled water to see if there is a difference in the plaque reducing effect.

Interventions

OTHERsesame-based oil

15min of oil pulling with 15ml sesame-based oil for 8 weeks

OTHERdistilled water

15min rinsing with 15ml distilled water for 8 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Yes

Inclusion criteria

age ≥ 18 years contractual capability the presence of ≥ 10 teeth, community periodontal index of treatment needs (CPITN) grade 1 or 2

Exclusion criteria

missing consent community periodontal index of treatment needs (CPITN) grade 0, 3 or 4 pregnancy or breastfeeding systemic diseases or conditions that are associated with an increased risk of infection or necessitate concomitant antibiotic therapy with dental treatment mental and behavioral disorders that impede (verbal) communication allergy against sesame(oil) intake of antibiotics 6 months prior to or during study duration intake of medication potentially influencing gingival inflammation or bleeding (e.g. anticoagulants, cortisone) infectious diseases (e.g. HIV, hepatitis B or C) fixed orthodontic appliances ongoing oil pulling or mouth rinsing adult guardianship insufficient nasal breathing

Design outcomes

Primary

Measure	Time frame
Rustogi Modified Navy Plaque Index (RMNPI)	first follow up after 4 weeks, full study duration 8 weeks

Secondary

Measure	Time frame
Gingival Index (GI)	first follow up after 4 weeks, full study duration 8 weeks
microbial analysis	first follow up after 4 weeks, full study duration 8 weeks
Oral Health Impact Profile (OHIP)	first follow up after 4 weeks, full study duration 8 weeks

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026