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The Impact of Dental Health on Complications During and Following Radiotherapy in the Head and Neck Region.

The Impact of Dental Health on Complications During and Following Radiotherapy in the Head and Neck Region.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06840639
Enrollment
750
Registered
2025-02-21
Start date
2024-01-01
Completion date
2025-01-01
Last updated
2025-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extracting Own Teeth, Head and Neck Neoplasms, Radiotherapy; Complications

Brief summary

Study the risk of complications after dental extractions in patients recieving radiotherapy.

Detailed description

Dental extractions before radiotherapy in the head and neck region is an established part of the treatment plan for patients with malignant disease. There are contradictory results in the literature regarding the importance timing and magnitude of extractions. It is important to minimize complications in this patient group since the regular therapy is already detrimental to the affected tissues. Patients were extracted from the ARTSCAN register were the population was followed for 4 years for several factors, including development of osteoradionecrosis. The aim is to evaluate which diagnoses are more prone to develop complications after extraction. If there is a relationship between occurrence of complication and magnitude of dental pathology.

Interventions

PROCEDUREDentoalveolar surgery

Surgery to extract teeth

Sponsors

Lund University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Malignant diagnosis * radiotherapy pre or postoperative

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Does dental extractions increase the risk for complications such as osteoradionecrosis?From diagnosis of head and neck pathology, approximately 1 month before start of radiotherapy, and to the end of the medical record which may be from one year after the oncologic treatment up to 26 years after oncologic treatment.Type of complication when extracting teeth in conjunction with radiotherapy.
Does dental pathology in extracted teeth correlate with development of osteoradionecrosis?From diagnosis of head and neck pathology, approximately 1 month before start of radiotherapy, and to the end of the medical record which may be from one year after the oncologic treatment up to 26 years after oncologic treatment.Are any specific dental pathology more prone to develop complications than others?

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026