Periodontal Disease, Periodontal Inflammation
Conditions
Keywords
periodontal pocket, periodontal disease, periodontal inflammation
Brief summary
The effect of both the mechanical treatment and the topical metronidazol in reduccing the inflammation and depth of the periodontal pockets were assessed on the first bicuspids.
Interventions
PROCEDURERoot scaling
Scaling and root planing is a deep cleaning below the gumline used to remove plaque and tartar that cover the root in the periodontal pockets. This intervention is carried out in both control and experimental sites
DRUGTopical Gel
A gel (experimental: metronidazole VS control: carbopol) is introduced in the recently cleaned periodontal pocket. The allocation of either experimental or control gel was distributed randomly, being masked both the patient and the clinician.
Sponsors
University of Salamanca
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Periodontal patients with all first premolars suffering from moderate periodontal pockets (\>4mm of probing depth)
Exclusion criteria
* No patients received antibiotics nor periodontal treatment in the previous 6 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probing depth | Both one month and three months after root scaling | Probing depth is assessed at 6 points around the first bicuspids (mesiovestibular, midvestibular, distovestibular, mesiolingual, midlingual, distolingual) |
| Mieloperoxidase ng/mL | Both one and three months after root scaling | The determination of the quantity of mieloperoxidase ng/mL was assessed from the crevicular fluid of the treated bicuspids |
Countries
Spain
Outcome results
None listed