Healthy Participants
Conditions
Brief summary
The goal of this interventional study is to understand the neural and behavioural bases of action simulation and its links with action execution in healthy volunteers. Hypotheses: Action simulation recruits neural networks that are largely similar to those activated by action execution, with some differences to avoid executing a movement while observing/imagining it. Participants will be tested with TMS while doing motor imagery or action observation.
Interventions
DEVICETranscranial Magnetic Stimulation Sham
Participants will be asked to perform various behavioral tasks involving the use of action observation or motor imagery. During these tasks, transcranial magnetic stimulation will be used.
Sponsors
Université Catholique de Louvain
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* healthy adult volunteers (more than 18 years old)
Exclusion criteria
* Participants taking anti-epileptic drugs * pregnant or breastfeeding women cannot participate in this study * people with a pacemaker * people with a cochlear implant * people with a metal part in the brain or any other medical implant in their body (pump, neurostimulator, valve,) cannot take part in this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Motor Evoked Potential (MEP) | For the duration of the participants' visit to the laboratory (max 2h30) | Evoked motor potentials will be measured throughout the experiment using surface electrodes on different muscles to measure changes in corticospinal excitability. |
Outcome results
None listed