Skip to content

Opioid Prescribing in the Emergency Department for Sickle Cell Disease

Differential Opioid Prescribing in the Emergency Department for Patients With Sickle Cell Disease: a Vignette-based International Randomised Trial.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06835335
Acronym
DOPED-SCD
Enrollment
1063
Registered
2025-02-19
Start date
2025-02-17
Completion date
2025-03-19
Last updated
2026-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Discrimination, Racial, Emergency Medicine, Pain Management, Sickle Cell Disease

Brief summary

This study consists of a clinical vignette presented to emergency physicians asking them what they would prescribe to a patient with acute abdominal pain.

Interventions

BEHAVIORALopioid prescription

The intervention consisted of a randomized questionnaire presenting a clinical case of a patient suffering from severe abdominal pain. The control case was "As an emergency physician in an adult emergency department, you are presented with the following patient: The patient is a 39-year-old non-smoking male/female with a history of Meniere's disease and an allergy to Bactrim. He/she presents with abdominal pain that began abruptly 2 hours ago and has persisted despite taking NEFOPAM 45 minutes ago. This is his first episode. His/her vital signs are blood pressure 140/66, heart rate 91, pulse ox 97%, temperature 36.8°C. He/she rates his/her pain as 8/10 without any analgesic position. On clinical examination he/she presents with localized epigastric tenderness. The rest of the abdomen is soft, painless and depressed. There are hydro-aeriform noises. No diarrhea or vomiting. The rest of the clinical examination showed no abnormalities.". In the intervention case, patient had history of S

Sponsors

Centre Hospitalier Universitaire de Nīmes
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Being a emergency physician

Exclusion criteria

* Working outside of Europe.

Design outcomes

Primary

MeasureTime frameDescription
Morphine prescriptionthrough study completion, an average of 1 yearThe proportion of patient for which physician would have prescribed morphine

Secondary

MeasureTime frameDescription
Analgesic prescription between groupsthrough study completion, an average of 1 yearTo compare analgesic prescription between groups
factors associated with differences in management between groupsthrough study completion, an average of 1 yearidentify factors associated with differences in management (urgency level, morphine prescription and computed tomography scan ordering)
Differences according to patient and practitioner genderthrough study completion, an average of 1 yearanalyze the difference in morphine treatment prescribed according to patient and practitioner gender

Countries

France, United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026