Acute Appendicitis
Conditions
Keywords
Clinical diagnosis of acute appendicitis
Brief summary
The aim of this study is to describe the proportion of pa-tients with normal preoperative inflammatorymarkers among patients with histopathologically proven acute appendicitis
Detailed description
2.4.1- Type of the study: prospective clinical trial study 2.4. 2- Study Setting: Assuit university hospital 2.4. 3- Study subjects: 1. Inclusion criteria: patients complain of Rt iliac pain with Us positive for acute appendicitis with WBCS normal . 2. Exclusion criteria: malignant mass cancer appendix mesenteric adentis cecal diverticulum salpingitis c. Sample Size Calculation: 50 cases 2.4.4 -Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, …): Lab WBCS count CRP level Neutrophil differential count Clinical correlation US findings and MSCT if needed
Interventions
PROCEDUREAppendectomy
Open surgery for appendix which is inflamed
Sponsors
Assiut University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
14 Days to 60 Days
Healthy volunteers
Yes
Inclusion criteria
Inclusion * Male or female patients é clinically diagnosed acute appendicitis with normal WBCS
Exclusion criteria
* complicated AA (perforation, peri appendicular abscess or suspicion of a tumor. 2\_inflammatory bowel diseases 3\_inability to co-operate and give informed consent 4\_diffuse peritonitis 5\_Patients with serious comorbid conditions DM & renal insufficiency, serum creatinine \> 150 μmol/l 6\_Pregnant & lactating patient 7\_Patients with advanced malignancies & pt on immunosuppressive drugs
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Surgery done if needed | Days of hospital reservation | Patient with acute appendicitis and normal WBCS count will be under observation for while but people with evidence on imaging and high inflammatory markers will go under surgery |
Countries
Egypt
Outcome results
None listed