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Steroid Treatment for Meatal Stenosis

Topical Steroid Treatment for Meatal Stenosis: Clinical Outcomes and Uroflowmetry Assessment of Treatment Success

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06834698
Enrollment
32
Registered
2025-02-19
Start date
2022-09-01
Completion date
2025-05-15
Last updated
2025-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meatal Stenosis

Brief summary

The goal of this observational study is to learn about the efficacy of topical steroid treatment for meatal stenosis. The main question it aims to answer is: Is steroid therapy effective for treatment of meatal stenosis? Participants already treated for meatal stenosis will be included.

Interventions

DRUGBetamethasone Cream

Betamethasone 0.1% cream was administered to the external meatus twice per day for a duration of 21 days.

PROCEDUREmeatotomy

In the event of steroid therapy failure, a meatotomy was performed under general anesthesia. The procedure involved squashing the ventral aspect of the pinpoint meatus for approximately 3-5 millimeters for 10 seconds and then incising it. The mucosal margins were sutured with absorbable sutures to avoid renarrowing. Urethral catheterization was not employed, and the procedure was performed on an outpatient basis. Patients were discharged following urination.

Sponsors

Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
No minimum to 16 Years
Healthy volunteers
No

Inclusion criteria

* Presence of meatal stenosis

Exclusion criteria

* Presence of any anatomical problem or history of surgery

Design outcomes

Primary

MeasureTime frameDescription
The number of patients who showed significant clinical improvement over the course of the study2 monthsThe resolution of symptoms such as straining, hesitancy, interrupted voiding, thin urine stream, and storage symptoms (e.g., urgency, frequency, urge incontinence) along with improved urination were considered indicators of treatment success. All patients underwent assessment through physical examination and observation of the urinary stream during micturition.

Secondary

MeasureTime frameDescription
The number of participants who exhibited treatment-related improvements in voiding curve pattern and maximal urine flow rate, as assessed by uroflowmetry, which measures the free flow of urine during micturition2 monthsUroflowmetry is a diagnostic test that evaluates the flow of urine during micturition (urination), providing valuable insights into bladder function and obstruction. The voiding curve pattern refers to the shape and flow characteristics of the urine stream during urination. A normal voiding pattern typically presents a bell shape, reflecting a steady and consistent flow of urine without interruptions. However, in certain conditions, such as urinary tract obstruction or bladder dysfunction, the voiding curve may become irregular, showing reduced flow or intermittent pauses. A plateau-shaped voiding curve is typically observed in conditions like meatal stenosis. Improvement in the voiding curve pattern following treatment indicates that urine flow has become more consistent and efficient. Maximal urine flow rate (Qmax) is the highest rate at which urine is expelled during micturition. This measurement is important for assessing bladder function and identifying potential urinary flow iss

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026