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Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location

Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location: Referring Oncology Hospital vs Other Hospitals.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06834646
Acronym
COVER
Enrollment
2000
Registered
2025-02-19
Start date
2025-04-12
Completion date
2026-09-01
Last updated
2026-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Cancer Remission

Keywords

Emergency Department, Cancer, Mortality, morbidity and mortality in Cancer

Brief summary

Patients being followed for cancer account for 2.8% of emergency admissions in France. An acute episode that triggers a visit to the emergency department may be related to the progression of the disease, or to complications of treatment. The management of these patients is often complex and requires a degree of expertise. Emergency departments specialising in the management of cancer complications have been set up, and now deal exclusively with patients treated at their centres. However, for geographical or logistical reasons, patients with cancer are likely to consult a non-specialist emergency department and/or one located outside the cancer care centre. In this case, the emergency doctor may not have access to the oncology file, and care in the emergency department and downstream services may be sub-optimal. Studies have shown a positive impact on the quality of care and prognosis of patients thanks to the cancer centre's expertise. However, the effect of the centre on a cancer patient who visits the emergency department has never been studied. This is particularly true if the emergency department where the patient is seen is located in the cancer follow-up centre. The primary objective of the COVER study is to investigate the impact of the location of the emergency department where the patient is seen for their prognosis.

Interventions

None listed

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients aged 18 or over admitted to an emergency department with cancer that has been active or in remission for less than a year.

Exclusion criteria

\- Opposition to participate in the study

Design outcomes

Primary

MeasureTime frame
Number of days alive spent outside the hospital1 month

Secondary

MeasureTime frameDescription
Occurrence of a new/ unscheduled consultation30 days
Length of hospitalisation90 day
Unscheduled consultation or hospitalization emergency department discharge7 days
Unexpected death7 days
Secondary admission to the intensive care unit during the initial hospitalization following the emergency visit7 days
Occurence of organ failure7 days
Quality of life with QLQ-C3090 daysQLQ-C30
Mortality30 days

Countries

France

Contacts

CONTACTYonathan FREUND, PU-PH
yonathan.freund@aphp.fr00 33 (0) 184827129
CONTACTOlivier PEYRONY, MD, PhD
olivier.peyrony@aphp.fr00 33 (0) 142494939

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026