Esophageal Cancer, Neoadjuvant Therapy
Conditions
Brief summary
This study aims to predict the efficacy of different types of neoadjuvant therapy and related postoperative pathological indicators in patients with esophageal cancer based on imaging parameters from CT and multimodal MRI, as well as clinical indicators collected before and after neoadjuvant treatment.
Interventions
None listed
Sponsors
Henan Cancer Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Consecutive patients with histopathological diagnosis of esophageal cancer. 2. Patients underwent neoadjuvant therapy before radical surgery for esophageal cancer: neoadjuvant chemotherapy, neoadjuvant chemoradiotherapy, neoadjuvant chemotherapy plus immunotherapy, neoadjuvant chemoradiotherapy plus immunotherapy. 3. All patients underwent CT and multimodal MRI examinations before and after neoadjuvant therapy. 4. The preoperative clinical data and postoperative pathological data are complete.
Exclusion criteria
1. Patients with other primary malignant tumors or previous anti-tumor treatment. 2. CT and MRI images with poor quality.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| CT and multimodal MRI in prediction of neoadjuvant therapy efficacy and postoperative pathological indicators in esophageal cancer | March 2025 - January 2030 | To evaluate the effectiveness of CT and multimodal MRI in determining the neoadjuvant therapy efficacy and postoperative pathological indicators in esophageal cancer. |
Contacts
Primary ContactJinrong Qu
Outcome results
None listed