Colonic Polypectomy in Cirrhotic Patients With Portal Hypertension

Challenges in Colonic Polypectomy and Endoscopic Mucosal Resection in Cirrhotic Patients With Portal Hypertension: Single-Center Experience

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06832826

Enrollment

Registered

2025-02-18

Start date

2024-01-14

Completion date

2025-03-30

Last updated

2026-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirrhosis, Polypectomy, Polyp of Colon, Portal Hypertension Related to Cirrhosis

Keywords

colonic polyp, polypectomy, portal hypertension, post-polypectomy bleeding

Brief summary

The goal of this retrospective cohort study is to evaluate the risk of post-polypectomy bleeding following the colonoscopy resection of lower gastrointestinal polyps in patients with liver cirrhosis with portal hypertension. The main question it aims to answer is: Does the risk of bleeding increase after colonoscopy polypectomy in patients with liver cirrhosis with portal hypertension? Participants will be subjected to polypectomy of any colonic polyps.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* All liver cirrhosis patients with portal hypertension and colonic polyps

Exclusion criteria

* Patients with platelet count less than 50,000/µL. * Patients with hemoglobin levels less than 8 g/dL. * Prothrombin Time more than 20 seconds.

Design outcomes

Primary

Measure	Time frame
Immediate post polypectomy bleeding (IPPB)	During procedure
Delayed post polypectomy bleeding (DPPB)	24 hours to 14 days

Secondary

Measure	Time frame	Description
Type of polyps in patients with liver cirrhosis and portal hypertension	14 days	Using the Paris classification system for polyps

Countries

Egypt

Contacts

STUDY_DIRECTORAyman Sadek, MD

Zagazig University

Outcome results