Parkinson
Conditions
Brief summary
This study aims to evaluate the impact of positive psychological intervention based on the PERMA model on Parkinson's disease patients by assessing their depression, quality of life, and related psychological indicators before and after intervention.
Interventions
BEHAVIORALRoutine nursing methods
According to their condition, they receive individualized drug treatment, including the main drugs of Parkinson's disease (such as dopamine replacement drugs) and combined antidepressant drugs. Secondly, regular follow-up evaluations will be conducted to monitor disease progression and drug side effects. At the same time, patients and their families will receive health education on Parkinson's disease and depression.The patients would receive basic psychological support. Medical staff will encourage patients to express their emotions and pay attention to their psychological state, which will help alleviate anxiety and depression. Medical staff will provide patients with information about local support organizations and social groups, and encourage patients to participate in related activities to increase social interaction and emotional support.
BEHAVIORALPERMA positive psychological intervention mode
(1) Formation of an intervention team.(2) Development and execution of interventions.The study group participated in a series of positive psychology workshop involving interviews and exercises aligned with the PERMA model as part of their routine health education. Each participant took part in individualized interviews focused on two specific topics each week until all subjects were covered, with each session lasting between 30 to 50 minutes. This interview phase continued for one month, conducted in the hospital ward.
Sponsors
First Affiliated Hospital of Wenzhou Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
42 Years to 81 Years
Healthy volunteers
No
Inclusion criteria
* Subjects must meet the clinical diagnostic criteria for primary Parkinson's disease * Subjects must not have a history of depression or other significant illnesses (e.g., stroke, coronary heart and tumor disease) * Subjects should have clear consciousness, effective communication capabilities, and basic comprehension and reading skills to complete routine assessments * The diagnosis of depression adhered to the ' Chinese Classification and Diagnostic Criteria for Mental Disorders ' (Revised Third Edition) * Subjectsshould not have schizophrenia * Subjects should not have substance abuse (alcohol, tobacco or other psychoactive substances)
Exclusion criteria
* Subjects with significant mental or cognitive impairment that communication or completion of scale assessments * Subjects exhibiting severe self-harm or suicidal tendencies * Subjects with severe dysfunction of the heart, liver, kidney or other critical organs * Subjects with contraindications for transcranial magnetic stimulation (such as cochlear implant, pacemaker, built-in pump, artificial metal heart valve, suspected metal in the eye or elevated intracranial pressure) * Subjects with a history of epilepsy that is poorly controlled * Subjects with Parkinson's disease who have undergone surgical treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the scores of Unified Parkinson's Disease Rating Scale(UPDRS) | before the intervention |
| the scores of Parkinson's Disease Quality of Life Scale(PDQ-39) | before the intervention |
| the scores of Hamilton Depression Scale(HAMD) | before the intervention |
| the scores of Hamilton Anxiety Scale(HAMA) | before the intervention |
| the scores of Connor-Davidson Resilience Scale(CD-RISC) | before the intervention |
| the scores of Pittsburgh Sleep Quality Index(PSQI) | before the intervention |
| the scores of Mini-Mental State Examination(MMSE) | before the intervention |
| the scores of Positive and Negative Affect Schedule (PANAS) | before the intervention |
| the Newcastle Nursing Satisfaction Scale score | before the intervention |
Countries
China
Outcome results
None listed