Coronary Artery Disease (CAD), Coronary Atherosclerosis, Heart Disease
Conditions
Keywords
NFL, Heart Disease
Brief summary
The GAMEFILM Registry is a post-market, multi-center, data collection study assessing the presence of CAD in NFL alumni.
Detailed description
The GAMEFILM Registry is a post-market, multi-center, data collection study assessing the prevalence and severity of CAD in NFL alumni. A retired NFL player is defined as any former player who made either a practice squad or an active NFL roster. Approximately 300 participants will be included from approximately 20 sites in the US.
Interventions
DIAGNOSTIC_TESTCoronary computed tomography angiography
Coronary Computed Tomography Angiography (CCTA) is a non-invasive medical imaging test that uses X-rays to create detailed 3D images of the heart and its blood vessels, specifically the coronary arteries.
Sponsors
HeartFlow, Inc.
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Retired NFL player
Exclusion criteria
* CCTA not successfully processed for FFRct and AI-Plaque
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Participants with CAD | 24 hours from the time CCTA was taken | The proportion of participants with coronary artery disease demonstrated on coronary computed tomography angiography (CCTA). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Participants with physiologically significant CAD | 24 hours from the time CCTA was taken | 1\. The proportion of participants with physiologically significant CAD (FFRct ≤ 0.80) |
| Participants with high coronary plaque burden | 24 hours from the time CCTA was taken | 2\. The proportion of participants with high coronary plaque burden (\>75th percentile for age- and sex-matched peers) |
Countries
United States
Contacts
Primary ContactHeartFlow
Outcome results
None listed