Kidney Disease, Chronic, Kidney Transplant
Conditions
Brief summary
An observational study capturing real world transplant patients in the post-operative setting aiming to further determine the utility of biomarkers to improve outcomes.
Detailed description
A prospective longitudinal observational study capturing patients receiving kidney transplants in Scotland. The primary objective is to assess whether there are clinical biomarkers present in the urine that determine the outcome of kidney transplants and predict early graft rejection.
Interventions
None listed
Sponsors
University of Edinburgh
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
Any patient within a Scottish Transplant centre who has undergone renal transplant (+/- pancreas/islet) and is due to attend routine follow-up appointments at the index centre.
Exclusion criteria
* no previous kidney transplant * patient attending follow-up at a peripheral site * unable to provide urine samples across the study duration
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants that experience acute transplant rejection | 12 months | Defined by gold standard core biopsy, reported using the Banff histology grading. |
Countries
United Kingdom
Contacts
CONTACTAlexander J Le Saint-Grant, MBChB
STUDY_CHAIRMarc Vendrell, PhD
University of Edinburgh
Outcome results
None listed