Diabetic Dyslipidemia
Conditions
Brief summary
To compare health-related physical fitness parameters in Type 2DM patients with and without dyslipidemia.Cardiometabolic biomarkers glucose and lipid profile will be noted from medical records. Body composition, functional capacity will be assessed with a six-minute walk test, peripheral muscle strength with a dynamometer, and physical activity level with a pedometer.
Interventions
None listed
Sponsors
Biruni University
Istanbul Galata University
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
35 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Having been diagnosed with Type 2 DM for at least 1 year, * Having an HbA1c value between 6.5-11%, * Being between the ages of 35-65, * Knowing how to read and write Turkish, * Having signed the informed consent form
Exclusion criteria
* Lack of cooperation * Patients with peripheral or central serious neurological disorders * Patients with uncontrolled hypertension and uncontrolled arrhythmia * Pregnant or lactating patients * Patients with diabetic ulcers or neuropathy * Chronic renal failure (eGFR\<30 ml/min) * Chronic liver disease (ALT/AST\<3X Upper limit of normal) * Patients with serious respiratory system disease * Patients with cardiac pacemakers * History of previous stroke or myocardial infarction * Presence of lower and upper extremity orthopedic problems that may prevent the application of clinical tests
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body fat-muscle ratios | 1 day | Body fat-muscle ratios;These measurements will be determined by bioelectrical impedance. |
| Funcitonal capacity | 1 day | Submaximal functional exercise capacity of the participants will be evaluated with the six-minute walk test. |
| Waist circumference | 1 day | Waist circumference will be measured at belly level with the patient in an upright position during expiration, with both feet bearing equal weight. |
| Hip circumference | 1 day | Hip circumference will be measured at the level of the greater femoral trochanter, with the patient in an upright position, with both feet bearing equal weight. |
| Muscle strength | 1 day | M. Quadriceps muscle strength and hand grip strength measurement will be used to evaluate peripheral muscle strength. Hand-held dynamometer will be used to evaluate quadriceps muscle strength and hand grip strength. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Glucose profile | 1 day | Glucose profile, including Hemoglobin A1c (HbA1c) was measured. Additionally, the glucose profile will be assessed after 12 hours of fasting using standard biochemical analysis. |
| Lipid profile | 1 day | Lipid profile, including low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), and total cholesterol, will be measured after 12 hours of fasting using standard biochemical analysis. |
| Physical activity level (step count) | 1 week (seven days) | Step Count Measurement: Daily step count will be monitored to determine the physical activity level of the participants.Step count will be assessed with a wearable activity monitor, a portable, easy-to-use tool that can measure objectively (pedometer). With its six-axis sensor, the device records the user's physical activity style information in its temporary memory throughout the duration of use. After one week of use, the data recorded with the wearable activity monitor will be taken. |
Countries
Turkey (Türkiye)
Outcome results
None listed