Neurodegenerative Diseases
Conditions
Brief summary
Datscan scintigraphy is a nuclear medicine examination allowing the diagnosis of neurodegenerative pathologies linked to damage to dopaminergic pathways, such as Parkinson's disease (essential for the differential diagnosis of essential tremor).
Detailed description
Datscan scintigraphy is a nuclear medicine examination allowing the diagnosis of neurodegenerative pathologies linked to damage to dopaminergic pathways, such as Parkinson's disease (essential for the differential diagnosis of essential tremor). There are several types of cameras allowing its performance: * Conventional Anger cameras and, * CZT (Cadmium-Zinc-Telluride) semiconductor cameras. At the Nancy University Hospital, the nuclear medicine department has a wide-field Cadmium-Zinc-Telluride camera: VERITON-CT (Spectrum Dynamics). The interpretation of this examination is purely visual. The objectives are therefore to: * Create the first international database of semi-quantitative values in 3D scintigraphy with Datscan performed with a VERITON-CT camera. * Compare this database with another database from a conventional Anger camera (Lyon Nuclear Medicine Department) to show its superiority.
Interventions
OTHERdatscan scintigraphy
Semi-quantitative analysis on Datscan imaging scintigraphy
Sponsors
Central Hospital, Nancy, France
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Adult patients who have undergone a Datscan scintigraphy on the VERITON camera in the nuclear medicine department of the Nancy University Hospital and who have an established clinical diagnosis, -Absence of neurodegenerative pathology or Parkinson's disease or Lewy body disease. * The clinical diagnosis can only be established after two years of clinical follow-up.
Exclusion criteria
* Excluded from this research will be the patients opposed to the use of their data, minors, atypical Parkinsonian syndromes, * patients who died before two years of clinical follow-up, * patients who had their Datscan examination carried out on a camera other than the VERITON and - patients lost to follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To create the first international database of Datscan by camera VERITON-CT. | One day | Fixation ratio of central gray nuclei of the brain namely, the global striatum, caudate nuclei, putamens |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Compare this database with another database from another type of camera (Lyon nuclear medicine team) to show its superiority. | One day | Identical to the primary evaluation criterion compared to those of the Lyon database. |
Countries
France
Outcome results
None listed