Amyotrophic Lateral Sclerosis
Conditions
Brief summary
In this study, we will evaluate how solo, naive listeners perceive the speech of people with amyotrophic lateral sclerosis (ALS) and age-matched speakers produced across interactive and non-interactive contexts with an unfamiliar, naive interlocutor.
Detailed description
Listeners will hear recorded speech of PALS and age-matched speakers and indicate what they heard. Recorded speech consists of vowels and consonants produced in non-interactive and interactive tasks. The perceptual judgements will be compared to see whether interactive contexts have similar perceptual effects across the two groups. Plans for Assignment - This is a single group study in which all participants will engage in the same tasks. Delivery of Intervention: Solo listeners will participate in this study in a remote, asynchronous format. They will be recruited using the online participant recruitment platform Prolific © and will use their own laptop/computer and headphones. Adequacy of Sample size: We will use n = 1300 listeners to achieve 80% power at alpha of .05 to detect between group differences with the assumption of medium effect sizes (Cohen's f = 0.3). Adequacy of Analyses: The proposed statistical analyses (Generalized mixed effects regressions) are standard and will be used to analyze the effect of the intervention on the outcome measures described below.
Interventions
BEHAVIORALListener judgements of speech produced in different tasks
Listeners will hear recorded speech of PALS and age-matched speakers across interactive and non-interactive tasks and indicate what they heard by clicking one of four words displayed on the screen. Standard attention checks and minimum performance thresholds (Theodore, 2021) will be used to ensure that listeners are engaged and are able to provide meaningful perceptual judgments.
Sponsors
Penn State University
National Institute on Deafness and Other Communication Disorders (NIDCD)
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Listeners will hear recorded speech of PALS and age-matched speakers and indicate what they heard. Recorded speech consists of vowels and consonants produced in non-interactive and interactive tasks. The perceptual judgements will be compared to see whether interactive contexts have similar perceptual effects across the two groups. Plans for Assignment - This is a single group study in which all participants will engage in the same tasks.
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* passing the remote hearing screening * having no known speech, language or neurological disorders per self-report * being a native monolingual speaker of American English * having no experience communicating with people with dysarthria * being between the ages of 18 and 65.
Exclusion criteria
* None - if volunteer meets the inclusion criteria, then they will be enrolled
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intelligibility of recorded speech | one 20 minute session | Perceptual judgments will be provided by solo, naïve listeners who did not participate in the interactions. Listeners will hear recorded speech of PALS and age-matched speakers recorded across the different tasks and indicate what they heard. The score will be expressed in percent. The possible range is between 0-100%. The higher scores mean a better outcome. |
Countries
United States
Contacts
CONTACTAnne Olmstead, Ph.D.
PRINCIPAL_INVESTIGATORJimin Lee, Ph.D.
The Pennsylvania State University
PRINCIPAL_INVESTIGATORNavin Viswanathan, Ph.D.
The Pennsylvania State University
PRINCIPAL_INVESTIGATORAnne Olmstead, Ph.D.
The Pennsylvania State University
Outcome results
None listed