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Influence of Sensory Electrical Stimulation on Hand Functions in Chronic Stroke Patients

Influence of Sensory Electrical Stimulation on Hand Functions in Chronic Stroke Patients

Status
Enrolling by invitation
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06826976
Acronym
SES-Hand
Enrollment
30
Registered
2025-02-14
Start date
2025-04-01
Completion date
2025-06-10
Last updated
2025-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke, Hand Functionality

Keywords

stroke, hand function, sensory electrical nerve stimulation, task specific training

Brief summary

This study investigates the impact of sensory electrical nerve stimulation (SENS) on hand function in chronic stroke patients. Thirty participants were randomly divided into two groups: Study Group (A): Received SENS combined with task-specific training. Control Group (B): Received only task-specific training. Assessments conducted before and after the intervention included measurements of grip strength, pinch strength, wrist range of motion, and performance on the Action Research Arm Test (ARAT).

Detailed description

This study explores the effectiveness of sensory electrical nerve stimulation (SENS) in enhancing hand function among chronic stroke patients. Thirty participants were randomly divided into two groups: Study Group (A): Received SENS combined with task-specific training. Control Group (B): Received only task-specific training. Assessment Methods: Before and after the intervention, both groups underwent evaluations using: Grip Dynamometer: To measure grip strength. Pinch Dynamometer: To assess pinch strength. Digital Goniometer: To determine wrist flexion and extension range of motion. Action Research Arm Test (ARAT): To evaluate upper limb functional performance.

Interventions

peripheral sensory electrical stimulation on median, ulnar, and radial nerves of affected upper limb, simultaneously with Task Specific Training program which included four subtests of Action Research Arm Test scale.

OTHERtask specific training program

received task specific training program only. Patients were tested pre and post treatment by Grip dynamometer, Pinch dynamometer, Digital goniometer and Action Research Arm Test Scale (ARAT).

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

In the context of the study on sensory electrical nerve stimulation (SENS) for chronic stroke patients, a parallel assignment model was utilized. Participants were randomly divided into two groups: Study Group (A): Received SENS combined with task-specific training. Control Group (B): Received only task-specific training. This design facilitated a direct comparison between the two groups to assess the added benefit of incorporating SENS into the rehabilitation program.

Eligibility

Sex/Gender
ALL
Age
40 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Patients who have experienced their first-ever ischemic stroke in the carotid system domain. * Age range: 40 to 65 years old. * Duration of illness: 30 to 180 days since stroke onset. * Spasticity of the affected hand muscles (wrist flexors, finger flexors, and finger adductors) must be grade 1+ or less according to the Modified Ashworth Scale. * Hand dysfunction severity ranges from mild to severe, defined by a score of ≤ 4 on the Medical Research Council Scale.

Exclusion criteria

* Presence of a deformity in the paralytic upper limb before the stroke. * History of a lower motor neuron lesion in the impaired upper extremity (e.g., polyneuropathy) before the stroke. * Skin abrasions or ulcerations on the affected upper limb. * Unstable health conditions, including cardiac dysfunction, end-stage renal failure, unstable diabetes, or uncontrolled hypertension (\>190/110). * Presence of a pacemaker or other implanted electrically sensitive devices. * Significant orthopedic conditions or chronic pain syndromes. * Chronic use of medications that may influence motor or sensory excitability (e.g., anti-epileptic or antipsychotic drugs). * Pregnancy.

Design outcomes

Primary

MeasureTime frameDescription
Hand grip strengthFrom enrollment to the end of treatment at end of 4th weekThe patient seated with his/her shoulder adducted and naturally rotated, elbow flexed at 90 degrees, forearm in neutral position, and wrist between 0- and 30-degrees dorsiflexion and between 0- and 15-degrees ulnar deviation. The Jamar hand dynamometer was set to the second handle position from the inside. Lightly hold around the readout dial to prevent inadvertent dropping. After the patient was positioned properly, the following statement was used Squeeze as hard as you can…. harder …. harder…. relax (16). The scores of three successive trials were recorded for each tested hand. The average score of three trials was compared to the normative data on the other side, which is in pounds.
wrist range of motionFrom enrollment to the end of treatment at end of 4th weekGoniometer was used to assess wrist flexion-extension.
pinch strengthFrom enrollment to the end of treatment at end of 4th weekThree types of pinches were typically evaluated because they are involved in accomplishing occupational tasks and activities efficiently. In Tip Pinch: The patient pinched the ends of the pinch meter between the tips of the thumb and index finger. The test was administered by first giving the patient instructions and a demonstration, Ready? Pinch as hard as you can. The patient was urged on as he or she attempted to pinch. The average of three trials was recorded. In Lateral Pinch (Key Pinch): The patient pinched the meter between the pad of the thumb and the lateral surface of the index finger. In Palmar Pinch (Three-Jaw Chuck): The patient pinched the meter between the pad of the thumb and the pads of the index and middle fingers
hand functionsFrom enrollment to the end of treatment at end of 4th weekPatients who achieve a maximum score on the first (most difficult) item are credited with having scored 3 on all subsequent items on that scale. If the patient scores less than 3 on the first item, then the second item is assessed. This is the easiest item, and if patients score 0 then they are unlikely to achieve a score above 0 for the remainder of the items and are credited with a zero for the other items. The maximum score on ARTS is 57 points (possible range 0 to 57).

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026