Comparative Factorial Study Design of Ultrasound Guided Wrist Block for Hand Surgery Comparing Effect of Bupivacane Alone and Bupivacane With Dexamethasone and Bupivacane With Dexametmiodine and Bupivacane With Dexamethasone and Dexametmiodine

A Comparative Factorial Study Design of Adjuvant Enhanced Ultrasound-Guided Wrist Block Anaesthesia for Hand Surgery : Bupivacane, Dexamethasone, Dexametmiodine

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06826690

Enrollment

160

Registered

2025-02-14

Start date

2025-03-30

Completion date

2026-03-30

Last updated

2026-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hand Surgeries

Brief summary

Ultrasound guided wrist block comparing effect of bupivacane alone and bupivacane with dexamethasone and bupivacane with dexametmiodine and bupivacane with dexamethasone and dexametmiodine

Detailed description

Ultrasound guided wrist block comparing effect of bupivacane alone and bupivacane with dexamethasone and bupivacane with dexametmiodine and bupivacane with dexametmiodine and dexamethasone. Taking medical and surgical history from patients. Taking base line data as heart rate and blood pressure and spo2. Measure duration of analgesia for post operative pain using NRS for 24 hours abd recording NRS at time interval of 2 , 4,6,12,24 hours post operative. Any patient the NRS above 4 will receive 5 mg nalbufin . Recording patients satisfaction by a survey .

Interventions

PROCEDUREGroup 1: ultrasound guided wrist block with bupivacane alone

Ultrasound guided wrist block with 15 ml volume of bupivacane.25%

PROCEDUREGroup 2 : ultrasound guided wrist block with bupivacane and dexamethasone

Group 2 : patients receive ultrasound guided wrist block with bupivacane.25% and 8 mg dexamethasone.. 15 ml volume totally

PROCEDUREGroup 3: ultrasound guided wrist block with bupivacane and dexametmiodine

Group 3 will receive ultrasound guided wrist block with bupivacane.25% and 50 mcg dexametmiodine... 15 ml volume totally

PROCEDUREGroup 4: patients will receive ultrasound guided wrist block with bupivacane and dexamethasone and dexametmiodine

Group 4 patients will receive ultrasound guided wrist block with bupivacan.25%e and 8 mg dexamethasone and 50 mcg dexametmiodine

Study design

Allocation

RANDOMIZED

Intervention model

FACTORIAL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

\- Patients more than or equal 18 years old and are ASA 1-3

Exclusion criteria

* allergy to used medication * pre exist neuropathy * coagulapthy * cognitive impairment * refusal to participate * Failed block and requiring general anesthesia

Design outcomes

Primary

Measure	Time frame	Description
dexamethasone × dexmedetomidine interaction on duration of postoperative analgesia, defined as the time from completion of the block to the first request for rescue analgesia.	defined as the time from block administration to first request of analgesia during the first 24 hour	defined as the time from block administration to first request of analgesia

Countries

Egypt

Contacts

STUDY_DIRECTORZaher Zaki Zaher, Specialist

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 18, 2026