Oxidative Stress, Polycystic Ovarian Syndrome (PCOS)
Conditions
Brief summary
The aim of the study was to determine changes in hematological and biochemical parameters and specific oxidative stress markers in patients with PCOS.
Interventions
None listed
Sponsors
Mardin Artuklu University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
The PCOS group included patients with oligomenorrhea (menstrual period intervals of more than 35 days), clinical signs of hyperandrogenism (acne or hirsutism), biochemical signs of hyperandrogenism (with total testosterone of 100 ng/dL and above and patients with dehydroepiandrosterone sulfate of 400 g/dl and above), an LH/FSH ratio of over 3 on the second day of the menstrual period, a body mass index of 25 and above, and polycystic ovaries detected in suprapubic ultrasonography.
Exclusion criteria
Pregnant individuals, individuals with diabetes mellitus, metabolic syndrome, adrenal pathology, pelvic mass, and malignancy were not included in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxidative stress markers | From January 2021 to December 2021 | TAS, TOS, OSI, PON, ARES, total thiol, native thiol, disulfide (-S-S-), reduced thiol, oxidized thiol, and IMA |
Countries
Turkey (Türkiye)
Outcome results
None listed