Functional Recovery, Motor Rehabilitation
Conditions
Brief summary
The present project aims to evaluate the facilitatory modulation of motor responses of the limb upper limb by tsDCS in patients with arm/hand hyposthenia after cerebral ischemia to verify the possible therapeutic benefits that this type of stimulation can induce in terms of of strength, dexterity and effectiveness in acts of daily living.
Interventions
OTHERtDCS
Transcranial direct current stimulation
Sponsors
IRCCS San Raffaele Roma
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Group Stroke: Inclusion criteria: 1. age over 18 years; 2. first ischemic/hemorrhagic stroke (within 30 days of onset); 3. mild-to-moderate stroke (NIHSS scale score\<16). 4. residual function of the upper limb, assessed by the following scales: - MRC of the distal muscles of the upper limb: score between 2 and 4; - NHISS (items 5A and 5B): score between 1 and 3; 5. ability to give informed consent and understand instructions.
Exclusion criteria
1. severe spasticity (Ashworth Scale score \> 2); 2. severe aphasia; 3. severe neglect; 4. history of disabling neurological disease; 5. history of epilepsy; 6. significant comorbidities; 7. contraindications to tsDCS. Healthy Group: Inclusion criteria: 1. age over 18 years; 2. equalized in age with the patient group.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| improvement of paretic hand performance | through study completion, an average of 1 year | The primary outcome measure is the improvement in hand strength and dexterity in individuals with upper limb motor impairment following cerebral ischemia, after the application of tsDCS at the cervical spinal level during Reaching |
Countries
Italy
Contacts
Primary ContactFabrizio Vecchio
Outcome results
None listed