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Investigation of the Cultural Adaptation, Validity, and Reliability of the Turkish Version of the CAP Questionnaire

Investigation of the Cultural Adaptation, Validity, and Reliability of the Turkish Version of the Central Aspects of Pain (CAP) Questionnaire

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06825650
Enrollment
300
Registered
2025-02-13
Start date
2024-11-28
Completion date
2027-11-28
Last updated
2025-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Back Pain, Fibromyalgia, Osteoarthritis

Keywords

nociplastic pain, central sensitization, back pain, osteoarthritis, fibromyalgia, pain

Brief summary

The CAP questionnaire, developed by modifying the CAP-Knee questionnaire to assess potential nociplastic pain features in painful musculoskeletal disorders, has been described. The CAP questionnaire is used in people with musculoskeletal pain and diagnostic subgroups of osteoarthritis, back pain, and fibromyalgia. There is no Turkish version of the CAP questionnaire. This study aims to investigate the cultural adaptation, validity, and reliability of the Turkish version of the CAP questionnaire.

Detailed description

Chronic pain is a symptom shared by many musculoskeletal conditions, even when disease management is optimized. Musculoskeletal pathologies are reported to be an essential therapeutic target in pain management. However, these pathologies often do not adequately explain the pain or the reason for its persistence. Central sensitization is the increased sensitivity of Central Nervous System (CNS) neurons to a standard nociceptive input. Pain that increases in intensity and distribution beyond that explained by musculoskeletal pathology has been termed nociplastic pain. Measuring these CNS aspects of pain is a prerequisite for understanding their mechanistic basis and predicting future pain and responses to treatment. Chronic pain is associated with CNS dysfunction in several areas, including depression, anxiety, pain catastrophizing, cognitive dysfunction, sleep disturbance, and fatigue. Considering the increasing importance of assessing mood-related pain (nociplastic pain) The CAP questionnaire, developed by modifying the CAP-Knee questionnaire to assess potential nociplastic pain features in painful musculoskeletal disorders, has been described.

Interventions

Questionnaire application

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* People with musculoskeletal pain and in diagnoses with OA, back pain, or FM * Above 18 years of age * Informed consent of the participant

Exclusion criteria

* Diagnosis of uncontrolled/other clinically significant diseases (chronic obstructive pulmonary disease, congestive heart failure, endocrine system diseases, neurological, psychological diseases, etc.) * Pregnant women

Design outcomes

Primary

MeasureTime frameDescription
Central Aspects of Pain Questionnaire (CAP)Three monthsThe CAP questionnaire consists of eight items assessing each of the eight characteristics linked to the central mechanisms of knee pain over the past week. These items assess neuropathic-like pain, fatigue, cognition, catastrophizing, anxiety, depression, sleep, and widespread pain.

Secondary

MeasureTime frame
Hospital Anxiety Depression Scale (HADS)Three months
Health Assessment Questionnaire (HAQ)Three months
BETY-Biopsychosocial QuestionnaireThree months
Central Sensitisation Inventory (CSI)Three months
Short-Form of McGill's Pain QuestionnaireThree months
Pain Catastrophizing Scale (PCS)Three months

Countries

Turkey (Türkiye)

Contacts

Primary ContactOrkun Tüfekçi, PT, PhD (c)
orkuntf@gmail.com5319502648

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026