Spinal Hypotension, Hypoperfusion
Conditions
Brief summary
Spinal anesthesia is a widely chosen technique in obstetric theaters due to several advantages, however sympathetic block results in hypotension that carry several consequences on maternal and fetal health, thus early prediction and management takes high priority. in this regards recent recommendations suggest the use of prophylactic vasopressors like noradrenaline, researchers of this study aimed to explore the impact of leg elevation on prophylactic noradrenaline dose
Detailed description
after spinal anesthesia, patients will be randomly allocated into 2 groups : Leg elevation group and control group. noradrenaline will be used as variable infusion starting from 0.05 microgram/kg/min up to 0.14 microgram /kg/minute. noradrenaline infusion will be continued till delivery of the baby
Interventions
DEVICELeg elevation
leg will be raised 30 degrees after spinal anesthesia using standardized pillow
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* full term * singleton pregnancy * ASA II
Exclusion criteria
* decline to participate * baseline SBP \<100 mmHg * failed spinal anesthesia * allergy to local anesthetic * coagulopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Average noradrenaline requirements | baseline to delivery of the baby | average noradrenaline requirements in both groups (mcg/kg/min) |
Secondary
| Measure | Time frame |
|---|---|
| Total noradrenaline requirements | baseline to delivery |
| incidence of spinal hypotension | baseline to delivery |
| incidence of severe hypotension | baseline to delivery |
Countries
Egypt
Outcome results
None listed