Bottle Feeding, Chronobiology, Human Milk/Breastfeeding, Preterm, Sleep Disorders, Circadian Rhythm
Conditions
Keywords
preterm Human milk Circadian rhythm neonate, sleep, cry
Brief summary
The ideal food for healthy term babies as well as preterm babies and sick term babies is breast milk. There are many studies showing that the composition of breast milk can vary from mother to mother, according to the baby's gestational age and gender. New studies on the content of breast milk suggest that breast milk is different during the day and at night, that micro and macronutrient content, hormones and some enzymes are secreted at different levels at different times of the day and that breast milk has a circadian rhythm. This study was designed as a prospective, randomized, controlled study. The study will be conducted to evaluate the effect of the Chronobiological Approach Feeding Model application on the baby's sleep characteristics and physiological conditions in preterm babies hospitalized in the Neonatal Intensive Care Unit (NICU). The simple randomization method will be used in the study and the babies will be divided into intervention (n=30) and control (n=30) groups. The study was conducted with 60 infants followed in the neonatal intensive care unit. The milk of the intervention group patients will be given to the babies by matching them circadianly , while the milk of the control group patients will be given without matching according to clinical routine practice. Demographic data and sleep measurements (time and quality) of all infants will be recorded in the Baby Monitoring Form created by the researcher.
Detailed description
Circadian fluctuations in breast milk content are very important in preterm infants fed with breast milk. The composition of breast milk changes throughout the day. There is no randomized controlled study in the literature suggesting that breast milk should be matched to the infant's circadian. This study aimed to evaluate the effect of the Chronobiological Nutrition Model application on the sleep characteristics and physiological conditions of preterm infants in the neonatal intensive care unit. It is aimed to increase the sleep duration and depth of infants, shorten the crying periods and increase the quality of nursing practices by circadian matching with breast milk in the feeding of preterm infants.
Interventions
PROCEDUREChronobiological Group
In the intervention group, a label containing the time of expressed breastmilk will be affixed. In the milk preparation room, breast milk will be stored in a separate refrigerator as 08:00-19:59 day milk and 20:00-07:59 night milk.
Sponsors
Istanbul Bilgi University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Investigator)
Intervention model description
Randomized Controlled two groups (control group and study group)
Eligibility
Sex/Gender
ALL
Age
32 Weeks to 37 Weeks
Healthy volunteers
Yes
Inclusion criteria
* Infants with family consent, * 32 0/6 - 36 6/7 weeks of gestation, * Exclusively breastfed, * Infants who have switched to full oral feeding
Exclusion criteria
* Intravenous fluid therapy, * Feeding intolerance * Sepsis, Necrotizing enterocolitis, Major congenital anomaly, * Mechanical ventilation support.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sleep time | 24 hour | Effect of Chronobiological Approach Feeding Model on infant sleep time during circadian matched breastfeeding sleep time in hours |
| Crying time | 24 hour | Effect of Chronobiological Approach Feeding Model on infant crying duration measured during circadian matched breastfeeding crying duration in hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Discharge time | through study completion, an average of 30 days] | The effect of Chronobiological Approach Nutrition Model application on infant's hospital stay |
Countries
Turkey (Türkiye)
Outcome results
None listed