Arthropathy of Knee, Aseptic Loosening
Conditions
Brief summary
The increase in life expectancy is leading to an increase in the average age of patients undergoing total knee arthroplasty (TKA), and, consequently, an increase in the number of revisions. The main cause of TKA failure is aseptic mobilization, which is described as the loss of integration between the prosthetic component and the bone in the absence of infection. This represents a significant impact on professional and economic resources for the Italian healthcare system. Aseptic mobilization can be caused by inadequate initial fixation of the implant and/or mechanical or biological loss of fixation over time, factors that often occur simultaneously. A careful, methodical evaluation of post-operative radiographs of TKAs remains an important diagnostic tool. The analysis of the causes of aseptic mobilization of TKAs and the associated economic impact in the Emilia Romagna region is useful for providing an estimate of the problem and identifying potential areas for improvement.
Interventions
None listed
Sponsors
Istituto Ortopedico Rizzoli
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients undergoing knee prosthesis revision for aseptic mobilization * Follow-up ≥ 2 years * Willingness to participate in the study * Both sexes * Patients ≥ 18 years old
Exclusion criteria
* Patient refusal to participate in the study and sign the informed consent * Simultaneous participation in other studies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Demographic data | 24 months | Collection of registry data related to the sample of patients undergoing TKA revision for aseptic mobilization, including demographic data |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Healthcare expenses | 24 months | Collection of data related to healthcare expenses resulting from aseptic mobilization (TKA revision surgery, length of stay, 90-day readmission rate, any other hospitalizations, etc.) |
| Radiographic analysis | 24 months | Radiographic analysis of the TKAs of patients who subsequently underwent revision surgery for aseptic mobilization at the II Orthopedic and Traumatological Clinic to assess the implant |
Countries
Italy
Outcome results
None listed