Dry Eye Disease
Conditions
Brief summary
Characterization of subjective discomfort/pain in patients with ocular surface dysfunction in association with clinical and laboratory parameters, for a better understanding of the underlying pathogenic mechanisms.
Detailed description
Dry Eye Disease (DED) is a multifactorial chronic disease impairing the ocular surface. DED can be associated with conditions of inflammation and neurosensory dysfunction. The aim of this study is to characterize the discomfort/pain in subjects affected by DED with the administration of scales, questionnaires, and analysis of corneal sensitivity by keratoesthesiometry, in association with clinical laboratory parameters.
Interventions
None listed
Sponsors
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* adult patients with suspected or diagnosed DED
Exclusion criteria
* nothing
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Discomfort in subjects affected by Dry Eye Disease (DED) | Baseline (enrollment visit) | Assessment of discomfort with Ocular Surface Disease Index (OSDI) and Dry Eye Questionaire-5 (DEQ-5) |
| Pain in subjects affected by Dry Eye Disease (DED) | Baseline (enrollment visit) | Assessment of pain with Visual Analogue Scale (VAS) and Numeric Rating Scale (NRS) |
Countries
Italy
Contacts
Primary ContactLuigi Fontana, MD
Outcome results
None listed