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Evaluation of Diagnosis and Treatment Methods in Corrosive Esophagitis: A 26-Year Experience-Based Algorithm

Evaluation of Diagnosis and Treatment Methods in Corrosive Esophagitis: Analysis of a 26-Year Experience-Based Algorithm

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06816758
Enrollment
501
Registered
2025-02-10
Start date
2025-05-01
Completion date
2025-05-15
Last updated
2025-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Diseases

Brief summary

This study aims to evaluate the diagnosis and treatment methods for corrosive esophagitis based on 26 years of clinical experience. It will retrospectively analyze patient records to identify patterns in clinical outcomes, complications, and the effectiveness of treatment strategies. The study focuses on optimizing patient care by proposing a diagnosis and treatment algorithm that can guide future clinical practices. Data will be collected from hospital archives and electronic health records, covering cases of corrosive esophagitis managed at Ondokuz Mayıs University between 1998 and 2024.

Interventions

OTHERRoutine Care for Corrosive Esophagitis

This is an observational study, so participants are not assigned interventions. However, the study investigates the outcomes of patients diagnosed with corrosive esophagitis who received routine clinical care. The exposure of interest includes diagnostic and treatment procedures such as endoscopic evaluation (Zargar classification), proton pump inhibitors, corticosteroid therapy, and surgical interventions for complications like strictures. The outcomes and clinical data collected reflect routine care practices over 26 years.

Sponsors

Caner İşevi, MD
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients diagnosed with corrosive esophagitis due to corrosive substance ingestion. * Hospitalized and treated at Ondokuz Mayıs University Thoracic Surgery Department. * Patients who underwent clinical, laboratory, and radiological evaluations to confirm the diagnosis. * Patients who were monitored and met follow-up criteria during their treatment. * Patients above 18 years of age

Exclusion criteria

* Patients under 18 years of age. * Patients who refused hospitalization or treatment. * Patients who ingested non-corrosive or non-toxic substances (verified by the Ministry of Health Poison Information Center). * Patients lost to follow-up or did not complete follow-up requirements. * Patients with incomplete data during the diagnostic or treatment process.

Design outcomes

Primary

MeasureTime frameDescription
Incidence of Esophageal Stricture, Perforation, and Other Related ComplicationsWithin 1 month after hospital admissionThe number of patients who develop esophageal strictures, perforation, or other complications within 1 month post-admission will be recorded.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026