Sleep
Conditions
Keywords
childhood,, psychomotor development, melatonin, actigraphy
Brief summary
Sleep is a neurophysiological active process essential for healthy physical and cognitive development. In Portugal, there is no recent and objective data on how children sleep. Given the importance of sleep in child health and development as well as the health gains achieved by establishing healthy sleep patterns since childhood, it seems extremely relevant to assess the various sleep parameters of Portuguese children and correlate them with their psychomotor and anthropometric development indicators. The results of this research work may support the implementation of sleep health education measures among parents, educators and policy makers, thus contributing to support the implementation of practices that promote sleep quality, napping until later in life as well as to promote the health of future adults.
Interventions
OTHERActigraphy
Actigraphy is a validated complementary means of diagnosis, the gold standard for the assessment of circadian rhythm.
OTHERSchedule of Growing Skills II
Assessment scale for skills in child development from 0 to 6 years.
OTHERQuestionnaire Children Sleep habits
Questionnaire for assessing sleep habits, validated for the Portuguese population (4) which allows us to understand the sleep hygiene habits of the child
OTHERMelatonin evaluation
Melatonin will be measured in the first-morning urine and it is considered to be a good marker of plasma MLT level since its concentration is highly correlated with nocturnal plasma melatonin.
Sponsors
Centro Hospitalar De São João, E.P.E.
Centro de Investigação em Tecnologias e Serviços de Saúde
Rede de Investigação em Saúde
Up2Kids Pediatric Center - Vila Nova de Gaia
USF Saúde no Futuro - Vila Nova de Gaia
Universidade do Porto
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to 4 Years
Healthy volunteers
Yes
Inclusion criteria
* Children aged 2 and 6 months year until the first assessment; * Gestational age at birth 37 weeks or more; * Delivery without serious complications for the child; * Absence of developmental pathologies or pathologies that interfere with psychic and motor development;
Exclusion criteria
* Non-preterm birth but with severe growth restriction; * Diagnosis of psychomotor development pathology; * Diagnosis of pathology that interferes with psychomotor development; * Taking daily medication, except vitamin supplements.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Melatonin levels | At 24 - 30 months of age, at 3 years of age and at 4 years of age | Levels of 6-sulphatoxymelatonin-aMT6, melatonin metabolite, measured in urine. |
| Sleep patterns | At 24 - 30 months of age, at 3 years of age and at 4 years of age | Sleep patterns based on movement tracking by sleep actigraphy. |
| Psychomotor development | At 24 - 30 months of age, at 3 years of age and at 4 years of age | The psychomotor developmental coefficient obtained through the application of the evaluation tool Schedule of growing skills II (SGS II) development scale. |
| Sleep hygiene | At 24 - 30 months of age, at 3 years of age and at 4 years of age | Sleep hygiene data obtained through the application of the Children Sleep habits questionnaire validated for the Portuguese population. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body Mass Index [BMI] | At 24 - 30 months of age, at 3 years of age and at 4 years of age | Weight \[kg, kilogram\] and height \[m, meter\] at the date of the evaluation for BMI-for-age calculation |
| Number of infectious events | At 24 - 30 months of age, at 3 years of age and at 4 years of age | Number of infectious events in the first year of life and previous year of the following assessments. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Demographics and lifestyle habits of the parents and family | At 24 - 30 months of age | Questionnaire about demographic parameters and lifestyle of the parents and family: Age group (less than 24 years; 24-29; 30-35; 35-40; more than 40); Household; Level of education; Profession; Shift work; Smoking habits; Diet (omnivore, vegetarian, ovolactovegetarian, vegan or other); Average bedtime; Average total sleeping time; Sleep schedules between weekdays and the weekend; Chronotype; History of sleep disturbances; Vitamin supplementation during pregnancy; History of postpartum depression. |
| Medical history and biometrics of the child | At 24 - 30 months of age | Questionnaire about the medical history and biometrics of the child: Gestational age at birth; APGAR index; Weight \[kg, kilogram\], length \[meter, m\] and head circumference \[centimeter, cm\] at birth; Type of feeding (breast milk, adapted milk or mixed feeding); Daycare attendance. |
Countries
Portugal
Contacts
Primary ContactAndreia Neves, PhDc
Backup ContactJanete Santos, PhD
Outcome results
None listed