Pain, Postoperative, Total Knee Replacement, Tourniquet
Conditions
Brief summary
Postoperative pain and blood loss of non-use compared to partial-use of a tourniquet in bilateral total knee replacement: A Randomized- Control Trial This study aimed to compare the effects of non-use (NTU) and partial-use (before osteotomy to skin closure; BOO) of a tourniquet in bilateral total knee arthroplasty (TKA) on postoperative pain and complications.
Detailed description
Despite numerous meta-analyses, and randomized-control trials (RCTs), there is still no conclusive evidence on the most effective, and efficient method of using a tourniquet. There is gap of knowledge of method of tourniquet usage. Hence this study will provide the best method to apply tourniquet.
Interventions
PROCEDURENone tourniquet
No tourniquet is used throughout the surgery.
Sponsors
Queen Savang Vadhana Memorial Hospital, Thailand
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Masking description
Outcome assessor will not know whether which group are using tourniquet.
Intervention model description
This study divided into 2 groups. This study was designed to compare the effect of NTU vs BOO in the patients underwent bilateral TKA. It is a crossover design to compare each knee in each group.
Eligibility
Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patients with over 50 years of age and diagnosed with bilateral severe knee osteoarthritis undergoing bilateral TKA
Exclusion criteria
* patients having undergone previous knee surgery * patients being subject to uncontrolled hypertension, coagulopathy, or recent knee sepsis * patients with an ASA physical status grade \> 2, * inability to use patient-controlled analgesia (PCA), such as communication, or cognitive issues, or those patients who were allergic to medications used in the treatment process.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain | At postoperative Day1,2,3,4 | Morphine consumption and Visual analog scale for pain minimum 0, maximum 10 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood loss | At postoperative Day1,2,3,4 | Pre operative hematocrit and post operative hematocrit change |
Countries
Thailand
Outcome results
None listed