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Lateral Sinus Augmentation Utilizing Bovine Bone Mixed with Platelet-rich Fibrin

Lateral Sinus Augmentation Utilizing Bovine Bone Mixed with Platelet-rich Fibrin: Evaluation of Graft Volume Changes Based on CBCT Imaging

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06810921
Enrollment
34
Registered
2025-02-06
Start date
2023-01-13
Completion date
2024-08-01
Last updated
2025-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lateral Sinus Lifting

Brief summary

Background: In sinus augmentation procedure, graft resorption remains a major dilemma of various graft materials. Objective: To estimate the graft volume changes following lateral sinus augmentation utilizing cone beam computed tomography. Methods: A total of 34 lateral sinus augmentation operations were performed and 50 dental implants were concomitantly inserted. The sinus augmentation cases were distributed randomly into 3 groups according to graft material: Group A comprised utilizing deproteinized bovine bone alone, group B using deproteinized bovine bone mixed with leukocyte and platelet-rich fibrin, and group C employing deproteinized bovine bone mixed with advanced platelet-rich fibrin. Cone-beam computed tomography was obtained 2 weeks (baseline record) and 24 weeks postoperatively for the measurement of the graft volume changes.

Interventions

PROCEDURElateral sinus lift

A rectangular shaped osteotomy was performed using a low-speed surgical handpiece and round diamond bur, with copious cooled normal saline irrigation. The Schneiderian membrane (SM) was gently elevatated using Frios Sinus Set elevators for implant placement

Sponsors

University of Baghdad
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* requiring lateral sinus lift for implant placement

Exclusion criteria

* available bone permits implant placement without need for sinus lifting

Design outcomes

Primary

MeasureTime frame
Evaluation of graft volume changes based on CBCT imaging24 weeks

Countries

Iraq

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026