Oral Lichen Planus
Conditions
Keywords
Oral Lichen Planus, Thyme Honey, triamcinolone acteonide
Brief summary
the study aimed to assess the effect of topical application of thyme honey in comparison to 0.1% triamcinolone acetonide oral paste on the relief of pain and clinical improvement in patients with OLP
Interventions
DIETARY_SUPPLEMENTthyme honey
Topical application on the oral mucosa
DRUGTriamcinolone Acetonide
Topical application on the oral mucosa
Sponsors
British University In Egypt
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
• Patients clinically and histopathologically (if required) diagnosed as suffering from OLP. * Patients free from any visible oral lesions other than OLP. * Patients who agreed to take supplied medications. * Patients who agreed for the biopsy (when required).
Exclusion criteria
• •Patients suffering from any systemic disease. * Treatment with any systemic treatment such as systemic steroids, other immunosuppressive drugs or non-steroidal anti-inflammatory drugs at least eight weeks. * Treatment with any oral topical medications for at least four weeks prior to the study. * Pregnant and lactating women. * In addition, no consideration was given to patients with a history of hypersensitivity to honey.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VAS score assessement | 1 month | Pain intensity |
Secondary
| Measure | Time frame |
|---|---|
| measurement of salivary level of miRna155 | 1 month |
Countries
Egypt
Outcome results
None listed