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Respiatory Viral Infections in Patients with Multiple Myeloma

Incidence and Clinical Significance of Respiratory Viral Infections in Patients with Multiple Myeloma

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06810115
Enrollment
219
Registered
2025-02-05
Start date
2015-10-01
Completion date
2024-10-01
Last updated
2025-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Mieloma, Respiratory Viral Infections

Keywords

Respiratory viral infections

Brief summary

Respiratory viruses are known to be a major cause of morbodity in multiple myeloma patients but prospective long-term sudies are lacking. We analysed 219 multiple myeloma patients that had 554 nasopharingeal swabs with 58 documented viral episodes. Respiratory viruses studied were rhinovirus, enterovirus, parainflienza, respirator, syncytial virus, metapneumovirus, coronavirus, bocavirus, influenza A, influenza B. Clinical data were extracted from a prospectively entered database, medical records were reviewed. We have prospectively studiend patients until May 2019 when we gathered survival data. Lastly because of Covid-19 pandemic when almost no other viral infections were isolated, we analysed clinical course of respiratory infections in patients with multiple myeloma after the pandemic.

Interventions

OTHERViral PCR test

Viral PCR test regardles of symptoms

Sponsors

University Medical Centre Ljubljana
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Patients with multiple myeloma

Exclusion criteria

Other hematological malignancies \-

Design outcomes

Primary

MeasureTime frame
Number of respiratory viral infections in patirnts with multiple myeloma1 year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026