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The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar

The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar(Split Mouth Technique)

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06809855
Enrollment
16
Registered
2025-02-05
Start date
2024-04-20
Completion date
2024-10-16
Last updated
2025-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dexamethasone Administration, Post Extraction Complication

Brief summary

Evaluating the effectiveness of using a single immediate postoperative intramuscular Dexamethasone injection on pain, swelling, trismus and tissue healing in the first seven days. Methods: A split mouth technique on 16 patients with bilateral similar impacted mandibular third molar were extracted; one side was given 8mg intramuscular injection of dexamethasone (study group) and the other side wasn't given injection (control group) and compare of the two sides were done in the following seven days.

Interventions

DRUGDexamethasone

single 8mg post-operative intramuscular injection

Sponsors

Yassir R. Al-khannaq
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Intervention model description

Each patient resembles the study group in which the patient is injected intramuscularly by a single dose 8mg dexamethasone immediate postoperatively after removal of impacted mandibular third molar on one side and control group on which the impacted mandibular third molar on the other side is removed without usage of 8mg dexamethasone.

Eligibility

Sex/Gender
ALL
Age
15 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

* bilateral similar impacted lower third molar * willing to do surgical extraction

Exclusion criteria

* Patients who are not fulfill the inclusion criteria * allergic to dexamethasone * who has medical diseases * taking any medications * pregnant or lactating women

Design outcomes

Primary

MeasureTime frameDescription
post operative pain changeseach participant was seen at 1st, 3rd and 7th post-operative daysmeasurement of change in pain on visual scale analog from 10 to 1 , 10 mean the worst pain and 1 is least pain
Change in post operative swellingeach participant was seen at 1st, 3rd and 7th post-operative daysThe swelling was measured between two points marked on skin in millimeters using ruler
Post operative Change in mouth openingeach participant was seen at 1st, 3rd and 7th post-operative daysThe distance between upper and lower incisors was measured in millimeters using ruler

Secondary

MeasureTime frameDescription
Tissue healingHealing was assessed on the 7th postoperative dayHealing of extraction site was assessed by using Landry, Turnbull and Howley index

Countries

Iraq

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026