Analgesia, Vastus Lateralis Nerve Block, Lateral Femoral Cutaneous Nerve Block, Knee Surgeries
Conditions
Brief summary
This study aims to compare the analgesic efficacy and functional outcomes of blocking the nerve to the vastus lateralis (NVL) muscle versus the lateral femoral cutaneous nerve (LFCN).
Detailed description
Knee surgeries are associated with significant postoperative pain, which can impede early mobilization and prolong recovery. Recent advancements in ultrasound-guided regional anesthesia have enabled more targeted nerve blocks, such as the blockade of the nerve to the vastus lateralis (NVL) and the lateral femoral cutaneous nerve (LFCN)
Interventions
DRUGVastus lateralis nerve block
Patients received vastus lateralis nerve block with 5 ml of bupivacaine 0.5%.
Patients received lateral femoral cutaneous nerve block with 5 ml of bupivacaine 0.5%.
Sponsors
Kafrelsheikh University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years. * Both sexes. * American Society of Anesthesiologists (ASA) physical status from I to III. * Underwent knee surgeries under spinal anesthesia.
Exclusion criteria
* Pregnancy. * Coagulopathy. * Neuromuscular disorders. * Hematological disorders. * Mental disorders. * History of multiple traumas or anesthesia drug allergies. * Local skin infection at the block site. * Body mass index (BMI) greater than 40. * Opioid analgesics or abusing opioids.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Degree of pain | 24 hours postoperatively | Each patient will be instructed about postoperative pain assessment using the numeric rating scale (NRS) score (0 represents no pain while 10 represents the worst pain imaginable). NRS assessments will be conducted at the post-anesthesia care unit (PACU) and at 2, 4, 6, 12, 18, and 24 hours postoperatively. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total morphine consumption | 24 hours postoperatively | If the numeric rating scale (NRS) exceeded 3, rescue analgesia in the form of a 3 mg morphine bolus will be administered, to be repeated after 30 minutes if the pain persisted until the NRS dropped below 4. |
| Block performance time | Intraoperatively | The block performance time will be recorded from the placement of the ultrasound probe to the removal of the needle after the injection of local anaesthetic. |
| Time to first request for analgesia | 24 hours postoperatively | The time to first request for analgesia will be recorded from the end of surgery till the first dose of morphine is administered. |
| Length of hospital stay | Till the discharge from hospital (Up to one week). | Length of hospital stay will be recorded from admission till discharge from the hospital. |
| Incidence of adverse events | 24 hours postoperatively | Incidence of adverse events such as postoperative nausea and vomiting (PONV), respiratory depression, and local anesthetic (LA) toxicity will be recorded. |
| Degree of patient satisfaction | 24 hours postoperatively | The degree of patient satisfaction will be measured using a 5-point Likert scale (1 = extremely dissatisfied, 2 = unsatisfied, 3 = neutral, 4 = satisfied, 5 = extremely satisfied). |
Countries
Egypt
Contacts
Primary ContactSherif K Arafa, MD
Outcome results
None listed