Chronic Periodontitis
Conditions
Keywords
Chronic periodontitis, Herbal Medicine, Low Level Laser Therapy, Adjunctive therapy, Acacia catechu
Brief summary
Evaluation of Acacia catechu and Low-Level Laser in the Treatment of Stage 2 Periodontitis.
Detailed description
* Assess the effectiveness of A. catechu gel (local delivery) adjunctive to non surgical therapy in the treatment of stage chronic periodontitis. Clinical and biochemical evaluation. * Compare the effectiveness of A. catechu gel (local delivery) and low-level laser adjunctive to non-surgical therapy in the treatment of stage chronic periodontitis. Clinical and biochemical evaluation.
Interventions
OTHERAcacia catechu
local delivery of acacia catechu gel in patient with chronic periodontitis stage 2
OTHERLow Level Laser Therapy
low-level laser as an adjunctive therapy in patient with chronic periodontitis stage 2
OTHERphase 1 therapy chronic periodontitis
patient with chronic periodontitis stage 2 will go for phase one therapy only
OTHERlocal drug delivary acacia +LLL
pateient with chronic periodontitis treated with LLL +acacia catehu gel
Sponsors
Faculty of Dental Medicine for Girls
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
1. Motivated patient with good oral hygiene. 2. Age ranges from (30-50) years. 3. Free from any systemic disease according to the Cornell Medical Index (16).
Exclusion criteria
1. Patients who received periodontal treatment over the 12 months preceding the study. 2. Patients who consumed antibiotics or anti-inflammatory drugs within the last 3 months. 3. Previous or current radiation or immunosuppressive therapies. 4. Pregnant & lactating women. 5. Patient with orthodontic appliances. Or having partial dentures. 6. Patient with parafunctional habits.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| inflammatory biomarker | 0 and 6 month evaluation | Measuring Interleukin 1 beta level |
| Antioxidant biomarker | 0 and 6 month evaluation | measuring total antioxidant capacity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| gingival index | 0,1,3,6 month evaluation | clinical evaluation of GI score from (0 to 3) 0 = normal is the best value. 3 = diseesed (the worst value). 0=Normal gingiva. 1. = mild inflammation, a slight change in color, slight edema, no bleeding on probing. 2. = moderate inflammation, redness, edema, and glazing; bleeding on probing. 3. = severe inflammation, marked redness and edema, ulceration, and the tendency to spontaneous bleeding. |
| clinical attachment level or loss | 0,1,3,6 month evaluation | * Clinical Attachment Level (CAL) or loss: Clinical attachment level was measured from the cementoenamel junction to the base of the pocket using a University of Michigan probe with the University of North Carolina periodontal probe (UNC15) around each tooth. * measurement unite by millimetre * zero clinical attachment level means no periodontitis * clinical attachment loss is a critical parameter differentiated betwwn gingivitis and periodontitis * the less the number, the better the case improvement. * cal of 2 mm is better than cal of 4 mm. |
| plaque index | 0,1,3,6 month evaluation | evaluation of PI score from (0-3) 0 is the best value; 3 is the worst. 0=No plaque is visible, even when a probe is used. 1. = Some plaque is visible only when a probe is used to skim the tooth surface. 2. = A visible amount of plaque can be seen without a probe. 3. = abudant amount of plaque at gingival margin, interdental spaces filled with plaque. |
Countries
Egypt
Outcome results
None listed