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LHC-CIDI-5 in Hong Kong

Use of Life History Calendars to Enhance Measurement of Lifetime Experience With Mental Disorders in Hong Kong.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06804525
Enrollment
2500
Registered
2025-02-03
Start date
2025-01-18
Completion date
2027-04-01
Last updated
2026-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Use Disorder (AUD), Bipolar I Disorder, Bipolar II Disorder, Bipolar Sub Disorder, Generalized Anxiety Disorder (GAD), Hypomanic, Intermittent Explosive Disorder (IED), Major Depressive Disorder (MDD), Major Depressive Episode (MDE), Manic Episode, Nonsuicidal Self-Injury, Obsessive-Compulsive Disorder (OCD), Panic Attack, Panic Disorder, PCL-5 PTSD, PCL-SC PTSD, Persistent Depressive Disorder (PDD), Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD), Suicidal Attempt, Suicidal Gesture, Suicidal Ideation, Suicidal Plan

Keywords

Life History Calendar, CIDI, Recall bias, Retrospective reporting, Lifetime prevalence, Mental disorders

Brief summary

The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10). However, retrospective measurements like the CIDI-5 are susceptible to recall bias, especially for the lifetime experience, which can hinder the reporting accuracy with mental disorders. To mitigate this issue, the life history calendar (LHC) was introduced as an aid to assist respondents in recalling the timing of life events, enhancing the ability of the CIDI-5 to measure the lifetime prevalence of mental disorders. The LHC is a grid structure with columns representing time units and rows representing life domains under study. In a study conducted in Nepal, combining the CIDI-5 with the LHC resulted in a significant increase in the detection of mental disorders compared to using the CIDI-5 alone. This approach did not lead to an increase in false positives after clinical validation. This experiment aims to adapt a Hong Kong version of the LHC based on the Nepalese model and evaluate the effectiveness of the LHC-assisted CIDI-5 (LHC-CIDI-5) compared to the CIDI-5 alone in assessing mental disorders.

Interventions

DIAGNOSTIC_TESTCIDI-5

The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10) . Trained interviewers will administrate selected modules from the Hong Kong version of the CIDI-5 in a computer-assisted personal interview to measure the outcomes.

DIAGNOSTIC_TESTLHC-CIDI-5

The interviewer will start by asking the respondent's age and significant personal experiences, which is expected to take 15 minutes. Remembering and recording the experiences provide cognitive engagement and information which can further serve as memory cues for respondents in the following screening of CIDI-5. Subsequently, the respondents will proceed to the screening section for CIDI-5 and will refer to the completed calendar from the LHC section when they are asked to report lifetime experience or age-of-onset for mental disorders. Trained interviewers will conduct all interviews in a computer-assisted personal interview. To validate the diagnoses in the LHC-CIDI-5 group, clinical re-interviews for MDD, GAD, and PTSD will be conducted by a trained mental health professional with previous experience using DSM-5.

Sponsors

The University of Hong Kong
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
25 Years to No maximum

Inclusion criteria

* All household members aged 25 years old and over are randomly sampled from the Census and Statistics Department List of Quarters * Live in the address sampled from the Census and Statistics Department List of Quarters * Reside in Hong Kong for at least six months in the past year * Able to read and communicate in Chinese or English * Without linguistic or cognitive difficulties

Exclusion criteria

* Domestic workers

Design outcomes

Primary

MeasureTime frameDescription
DepressionImmediately following intervention or recruitmentThe main outcomes in this module are the lifetime prevalence of Major Depressive Episode (MDE) and Major Depressive Disorder (MDD)
Persistent DepressionImmediately following intervention or recruitmentThe main outcome in this module is the lifetime prevalence of Persistent Depressive Disorder (PDD)
Self HarmImmediately following intervention or recruitmentThe main outcomes in this module are the lifetime prevalence of Suicidal Ideation, Suicidal Plan, Suicidal Attempt, Suicidal Gesture, and Nonsuicidal Self-Injury.
High MoodImmediately following intervention or recruitmentThe main outcomes in this module are the lifetime prevalence of Manic Episode, Hypomanic, Bipolar I Disorder, Bipolar Sub Disorder, and Bipolar II Disorder
Worry and AnxietyImmediately following intervention or recruitmentThe main outcome in this module is the lifetime prevalence of Generalized Anxiety Disorder (GAD)
Anger AttacksImmediately following intervention or recruitmentThe main outcome in this module is the lifetime prevalence of Intermittent Explosive Disorder (IED)
Panic AttacksImmediately following intervention or recruitmentThe main outcomes in this module are the lifetime prevalence of Panic Attack and Panic Disorder.
Obsessions and CompulsionsImmediately following intervention or recruitmentThe main outcome in this module is the lifetime prevalence of Obsessive-Compulsive Disorder (OCD)
Stressful ExperiencesImmediately following intervention or recruitmentThe main outcomes in this module are the lifetime prevalence of Posttraumatic Stress Disorder (PTSD), PCL-SC PTSD, and PCL-5 PTSD.
Tobacco, Alcohol, and DrugsImmediately following intervention or recruitmentThe main outcomes in this module are the lifetime prevalence of Alcohol Use Disorder (AUD) and Substance Use Disorder (SUD)

Countries

Hong Kong

Contacts

CONTACTYoona Kim, PhD
yoonak@hku.hk852+39179109
CONTACTRusi Long, MHS
rlong36@hku.hk852+39102308
PRINCIPAL_INVESTIGATORMichael Y. Ni, MD

The University of Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 11, 2026